Clinical Sciences Core Research Plan (C)

临床科学核心研究计划（C）

• 批准号: 8465179
• 负责人: Margaret A Fischl
• 金额: $ 25.8万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8465179
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Advisory Committees; Applications Grants; Area; Award; Behavioral; Behavioral Research; Biological; Biometry; Blood; Cancer Center Support Grant; Centers for Disease Control and Prevention (U.S.); Clinical; Clinical Data; Clinical Research; Clinical Sciences; Clinical Services; Clinical Trials; Cohort Studies; Collaborations; Community Outreach; Complement; Consent Forms; Consult; Data; Data Analyses; Data Set; Detection; Development; Devices; Disease; Drug Industry; Education; Enrollment; Epidemiology; Evolution; Fostering; Funding; Generations; Goals; Good Clinical Practice; Grant; Growth; HIV; HIV Infections; Head; Human; Human Resources; Industry; Institutes; Institutional Review Boards; Interdisciplinary Study; Investigational Drugs; Laboratories; Leadership; Left; Life Cycle Stages; Manuscripts; Medical; Methodology; Mission; Monitor; Pathogenesis; Phase; Pilot Projects; Play; Population; Predictive Factor; Preparation; Prevention; Prevention Research; Productivity; Recombinants; Research; Research Design; Research Infrastructure; Research Personnel; Research Priority; Resource Sharing; Rights; Role; Safety; Sample Size; Science; Scientist; Services; Social Welfare; Specimen; Staging; Statistical Methods; Therapeutic Human Experimentation; Tissues; Training; Translational Research; United States Health Resources and Services Administration; United States National Institutes of Health; Universities; Vaccine Research; Viral; abstracting; assay development; base; behavioral/social science; experience; human data; human subject; human tissue; innovation; institutional biosafety committee; meetings; member; multidisciplinary; preclinical study; protocol development; repository; research facility; response; sample collection; social; success

The Clinical Sciences Core will be led by Dr. Margaret FischI as Director, Dr. Charles Mitchell as Co- Director, and Dr. Kristopher Arheart as Biostatistical Subcore leader. The Clinical Sciences Core (CSC) during the past four years provided essential services that both enhanced the productivity and capacity of Miami CFAR investigators and new/young investigators and fostered collaborative research among clinical, behavioral/social, and basic scientists that involved human subjects, human data, and biological specimen collection and distribution. The CSC provided support and services to over 80 investigators for over 120 projects support by 7 NIH institutes, 6 NIH funded networks, the CDC, the HRSA, and the pharmaceutical industry and to over 100 CFAR members including young/new investigators. The mission of the CSC is to provide scientific leadership and infrastructure support that advances multidisciplinary collaborative research in basic, clinical, epidemiologic, behavioral/social, and translational sciences in the prevention, detection, treatment, and cure of HIV/AIDS. The mission and goals of the CSC are needs base driven by the research priorities of the UM CFAR investigators and their projects and by the CSC priority to foster synergy and produce an economy of scale. The CSC will focus on enhancing the capacity for HIV/AIDS research in NIH Networks, promoting and supporting innovative NIH HIV/AIDS research initiatives, and facilitating and promoting scientific interactions between CFAR investigators and industry. The CSC will accomplish this through the provision of Biostatistical study design expertise and biostatical services, provision of clinical data and biological specimen repository to foster collaborative immunopathogenesis research, assistance with IRB and regulatory agency submissions, and provision of state-of-the-art clinical research facilities with clinical services. The CSC is essential to the continued growth and success of the Miami CFAR, as it has provided critical expertise and services for advancing multidisciplinary clinical translation research in therapeutic, vaccine and prevention research that is not duplicated by other Cores or facilities at the University of Miami.

临床科学核心将由玛格丽特·菲斯基博士担任主任，查尔斯·米切尔博士担任联席主任，克里斯托弗·阿哈特博士担任生物统计学分核心负责人。在过去的四年中，临床科学核心(CSC)提供了基本的服务，提高了迈阿密CFAR研究人员和新/年轻研究人员的生产力和能力，并促进了临床、行为/社会和基础科学家之间的合作研究，涉及人类受试者、人类数据和生物标本的收集和分发。CSC为80多名调查人员、7个NIH研究所、6个NIH资助网络、CDC、HRSA和制药业支持的120多个项目提供了支持和服务，并向CFAR 100多名成员提供了支持和服务，其中包括年轻的/新的调查人员。 CSC的使命是提供科学领导和基础设施支持，促进基础、临床、流行病学、行为/社会和转化科学在预防、检测、治疗和治愈艾滋病毒/艾滋病方面的多学科合作研究。CSC的使命和目标是以需求为基础的，由UM CFAR调查员及其项目的研究优先事项以及CSC促进协同作用和产生规模经济的优先事项驱动。CSC将重点加强NIH网络中的艾滋病毒/艾滋病研究能力，促进和支持创新的NIH艾滋病毒/艾滋病研究倡议，并促进和促进CFAR调查人员与行业之间的科学互动。CSC将通过提供生物统计研究设计专业知识和生物统计服务、提供临床数据和生物标本库以促进协作的免疫发病研究、协助IRB和监管机构提交文件，以及提供最先进的临床研究设施和临床服务来实现这一目标。 CSC对于迈阿密CFAR的持续发展和成功至关重要，因为它为推进治疗、疫苗和预防研究中的多学科临床翻译研究提供了关键的专业知识和服务，这是迈阿密大学的其他中心或设施无法复制的。