Social Determinants Predicting Trajectories of HIV with Recent Latina Immigrants

预测近期拉丁裔移民艾滋病毒感染轨迹的社会决定因素

• 批准号: 8552051
• 负责人: Frank R Dillon
• 金额: $ 18.1万
• 依托单位: FLORIDA INTERNATIONAL UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8552051
• 关键词: 21 year old; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Adult; Age; Alcohol or Other Drugs use; Alcohols; Attenuated; Blood; Cause of Death; Chronic Disease; Communities; Data; Daughter; Development; Diagnosis; Disadvantaged; Drug Addiction; Drug abuse; Factor Analysis; Fatal Outcome; Fathers; Florida; Funding; Goals; HIV; HIV risk; Health; Health Services; Health Services Accessibility; Healthcare; Hepatitis; High Risk Woman; Ice; Immigrant; Incidence; Individual; Infection; Instruction; International; Intervention; Interview; Laboratories; Latina; Latino; Lead; Longitudinal Studies; Mental disorders; Modeling; Mothers; Outcome; Parents; Persons; Pharmaceutical Preparations; Prevention program; Prevention strategy; Preventive Intervention; Process; Questionnaires; Research; Resources; Risk; Risk Behaviors; Risk Factors; Saliva; Services; Severities; Social Policies; Substance Use Disorder; System; Testing; Triiodothyronine; United States; Universities; Urine; Woman; base; community based participatory research; community organizations; follow-up; high risk; high risk behavior; indexing; innovation; instrument; overdose death; peer; resilience; screening; social; sound

This proposed community-based participatory research subproject is part of our P20 competitive renewal application of the NIMHD-funded Center for Substance Use and AIDS Research on Latinos in the United States (C-SALUD) at Florida International University (FIU). The proposed longitudinal study consists of 4-annual assessments of recent Latina immigrants (N=600; ages of 18-23). By partnering with local community-based organizations, our multi-disciplinary research team will: (1) elucidate culturally relevant antecedent social determinants of liability (consisting of individual, cultural, interpersonal and community/institutional determinants collectively referred to as social determinants) which predict HIV/AIDS risk behaviors (HIVR), concomitant substance use severity (SUS), HIV/AIDS diagnoses, substance use disorders (SUDs) and access to health care resources (HCR), (2) determine the moderating effects of dyadic attachments (daughter-father, daughter-mother, daughter-peers, daughter-romantic partner) on the relationship between adverse social determinants and early adult trajectories of HIV/AIDS risk behaviors and SUS, (3) clinically validate outcomes with laboratory tests (saliva, urine and blood) for alcohol plus 9-drug classes, HIV-EIA and STDs and (4) create a psychometrically sound and culturally relevant screening instrument derived from the obtained results (Latina Screening Index of Risk and Resilience-LaSIRR) which may be employed to identify recent Latina immigrants at high risk to succumb to HIV/AIDS and SUDs. Longitudinal statistical analyses will capture dynamic system interactions between change processes and causal networks to elucidate interactions among the modeled variables across 4-annual waves. Factor analyses will be applied to data obtained at baseline assessment to derive a preliminary LaSIRR to predict HIV and SUD outcomes across 3 follow-up assessments.

这个以社区为基础的参与性研究子项目是美国佛罗里达国际大学（FIU） nimhd资助的美国拉丁美洲人药物使用和艾滋病研究中心（C-SALUD）的P20竞争性更新申请的一部分。提出的纵向研究包括对最近的拉丁裔移民（N=600，年龄在18-23岁）进行4年一次的评估。通过与当地社区组织合作，我们的多学科研究团队将：(1)阐明与文化相关的问题