Social Determinants Predicting Trajectories of HIV with Recent Latina Immigrants

预测近期拉丁裔移民艾滋病毒感染轨迹的社会决定因素

• 批准号: 8702932
• 负责人: Frank R Dillon
• 金额: $ 19.19万
• 依托单位: FLORIDA INTERNATIONAL UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8702932
• 关键词: 21 year old; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Adult; Age; Alcohol or Other Drugs use; Alcohols; Attenuated; Blood; Cause of Death; Chronic Disease; Communities; Data; Daughter; Development; Diagnosis; Disadvantaged; Drug Addiction; Drug abuse; Factor Analysis; Fatal Outcome; Fathers; Florida; Funding; Goals; HIV; HIV risk; Health; Health Services; Health Services Accessibility; Healthcare; Hepatitis; High Risk Woman; Ice; Immigrant; Incidence; Individual; Infection; Instruction; International; Intervention; Interview; Laboratories; Latina; Latino; Lead; Longitudinal Studies; Mental disorders; Modeling; Mothers; Outcome; Parents; Persons; Pharmaceutical Preparations; Prevention program; Prevention strategy; Preventive Intervention; Process; Questionnaires; Research; Resources; Risk; Risk Behaviors; Risk Factors; Saliva; Services; Severities; Social Policies; Substance Use Disorder; System; Testing; Triiodothyronine; United States; Universities; Urine; Woman; base; community based participatory research; community organizations; follow-up; high risk; high risk behavior; indexing; innovation; instrument; overdose death; peer; resilience; screening; social; sound

This proposed community-based participatory research subproject is part of our P20 competitive renewal application of the NIMHD-funded Center for Substance Use and AIDS Research on Latinos in the United States (C-SALUD) at Florida International University (FIU). The proposed longitudinal study consists of 4-annual assessments of recent Latina immigrants (N=600; ages of 18-23). By partnering with local community-based organizations, our multi-disciplinary research team will: (1) elucidate culturally relevant antecedent social determinants of liability (consisting of individual, cultural, interpersonal and community/institutional determinants collectively referred to as social determinants) which predict HIV/AIDS risk behaviors (HIVR), concomitant substance use severity (SUS), HIV/AIDS diagnoses, substance use disorders (SUDs) and access to health care resources (HCR), (2) determine the moderating effects of dyadic attachments (daughter-father, daughter-mother, daughter-peers, daughter-romantic partner) on the relationship between adverse social determinants and early adult trajectories of HIV/AIDS risk behaviors and SUS, (3) clinically validate outcomes with laboratory tests (saliva, urine and blood) for alcohol plus 9-drug classes, HIV-EIA and STDs and (4) create a psychometrically sound and culturally relevant screening instrument derived from the obtained results (Latina Screening Index of Risk and Resilience-LaSIRR) which may be employed to identify recent Latina immigrants at high risk to succumb to HIV/AIDS and SUDs. Longitudinal statistical analyses will capture dynamic system interactions between change processes and causal networks to elucidate interactions among the modeled variables across 4-annual waves. Factor analyses will be applied to data obtained at baseline assessment to derive a preliminary LaSIRR to predict HIV and SUD outcomes across 3 follow-up assessments.

这个拟议的基于社区的参与性研究子项目是我们在佛罗里达国际大学(FIU)由NIMHD资助的美国拉丁裔物质使用和艾滋病研究中心(C-Salud)P20竞争续签申请的一部分。拟议的纵向研究包括对最近的拉丁裔移民(N=600；年龄18-23)进行的4年一次的评估。通过与当地社区组织的合作，我们的多学科研究团队将：(1)阐明与文化相关的 责任的先行社会决定因素(包括个人、文化、人际和社区/机构决定因素，统称为社会决定因素)预测艾滋病毒/艾滋病危险行为(HIVR)、伴随物质使用严重程度(SUS)、艾滋病毒/艾滋病诊断、物质使用障碍(SUDS)和获得卫生保健资源(HCR)；(2)决定二元依恋(女儿-父亲、女儿-母亲、女儿-同伴、女儿-恋人)对 不良社会决定因素与艾滋病毒/艾滋病危险行为的早期成人轨迹和SUS之间的关系，(3)通过实验室测试(唾液、尿液和血液)临床验证酒精加9种药物类别、艾滋病毒-EIA和性传播疾病的结果，以及(4)根据所获得的结果创建心理测量学和文化相关的筛查工具(拉美风险和复原力筛选指数-LaSIRR)，该筛查工具 可能被用来识别最近死于艾滋病毒/艾滋病和肥皂泡的高风险拉丁裔移民。 纵向统计分析将捕捉变化过程和因果网络之间的动态系统相互作用，以阐明跨4年波的建模变量之间的相互作用。将对基线评估获得的数据进行因子分析，以得出初步的LaSIRR，以预测3次后续评估的艾滋病毒和SUD结果。