Acoustic Plus Electric Hearing

声学加电助听器

• 批准号: 8300336
• 负责人: CHRISTOPHER W TURNER
• 金额: $ 23.66万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-01-01 至 2017-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8300336
• 关键词: Acoustics; Agreement; Belief; Biological Preservation; Clinical Research; Cochlea; Cochlear Implants; Cochlear implant procedure; Collaborations; Data; Devices; Electric Stimulation; Electrodes; Electrophysiology (science); Esthesia; Frequencies; Future; Goals; Grant; Hearing; Hearing Aids; High-Frequency Hearing Loss; Hybrids; Implant; Iowa; Knowledge; Light; Literature; Location; Maps; Measures; Neuronal Plasticity; Patient Care; Patients; Performance; Qualifying; Recruitment Activity; Research; Residual state; Speech; Time; Translational Research; Work; clinical practice; design; hearing impairment; improved; patient population; speech recognition; success; transmission process

Project 1: Acoustic Plus Electric Hearing Preservation of residual acoustic hearing during cochlear implantation has become an important improvement in the performance of cochlear implants. Not only does it improve the performance of implants (particularly for noisy, real-world listening conditions) but also allows the treatment of patients with severe high-frequency hearing loss, who have substantial low-frequency hearing. This project proposes to continue this work on combining acoustic plus electric (A+E) hearing. In addition to the overall goal of improving patient care for hearing loss, several unique research opportunities arise from this work. The first opportunity arises because of the new population of patients that will be implanted with these A+E devices. Never before have patients with such high levels of pre-operative residual hearing been implanted in such a large- scale project. We are at the same time seeing levels of performance for the transmission of speech through the short electrode that are surprising in light of the previous literature. This will allow us to re-examine some of the commonly held beliefs about the limitations of electric stimulation due to channel interaction. The second opportunity arises because the short-electrode Hybrid implant assigns low- and mid-frequency speech bands to extreme basal locations in the cochlea. Thus we have a unique opportunity to study the effects of remapping, neural plasticity, and adaptation to highly-distorted place-frequency maps in the cochlea.

项目1：声学加电听觉 人工耳蜗植入术中残余听力的保护已成为人工耳蜗植入术的重要内容。 人工耳蜗性能的改善。它不仅提高了植入物的性能 （特别是对于嘈杂的、真实世界的听力条件），而且还允许治疗患有严重听力障碍的患者。 高频率听力损失，谁有大量的低频听力。该项目建议继续进行 这项工作结合了声学加电（A+E）听力。除了改善的总体目标外， 病人护理听力损失，几个独特的研究机会，从这项工作中产生。先机 由于将植入这些A+E器械的新患者人群而出现。从未 在此之前，具有如此高水平的术前残余听力的患者被植入如此大的- 规模项目。同时，我们也看到了语音传输的性能水平， 根据先前的文献，短电极是令人惊讶的。这将使我们能够重新审视一些 关于电刺激由于通道相互作用而受到限制的普遍看法。的 第二个机会出现，因为短电极混合植入物分配低频和中频 语音带到耳蜗中的极端基底位置。因此，我们有一个独特的机会来研究 重映射，神经可塑性和适应高度扭曲的位置频率图的影响， 耳蜗