The Effect of ScanCap Technology on Medication Adherence and Hypertension Outcome

描述（由申请人提供）：在这个II期SBIR项目中，康康斯健康解决方案（CHS）将继续开发ScanCap系统，并测试其对依从率和高血压患者预后的有效性。ScanCap系统是一个电子提醒帽，在药房无缝编程，并合并到处方药的原始包装中。最终产品还将能够记录服药时间，并将这些信息反馈给护理人员和医疗保健合作伙伴，以提高患者的服药依从性。II期研究的具体目标是：目标1：制造ScanCap并完成硬件和软件的开发，以收集存储在设备上的数据；目的2：确定与安慰剂帽相比，ScanCap是否可以改善药物依从性；目标3：确定是否可以通过使用ScanCap与安慰剂帽相比改善血压控制。改善药物依从性是几个NIH研究所当前的重点领域，符合NIH延长健康寿命和减少疾病和残疾负担的使命。扫描帽的设计制造成本约为2美元/单位，大批量生产，包括一个无线接口，可在药房自动编程；剂量到期时的视觉和听觉提醒；以及记录服药剂量并将患者用药记录无线传输到电子数据库的能力。它体积小，便于携带，设计适用于标准处方瓶和安全帽的功能。未来的功能将包括连接智能手机进行实时提醒。在第二阶段结束时，CHS将制造ScanCap电子提醒帽和数据收集系统的原型。CHS还将证明使用ScanCap系统的患者对药物依从性和血压控制的影响。对许多患者来说，适当遵守处方药物治疗方案可以改善整体健康状况并降低医疗费用。然而，典型的药物依从率低于50%，原因有很多，有些是有意的，有些是无意的，比如健忘和混乱。现在市场上的提醒设备不作为原始处方包装的一部分，让患者自己整理和实施非处方提醒产品。一个易于使用的提醒帽，适合标准的处方瓶将给药剂师一个工具，以帮助他们的病人药物剂量时间表。将提醒设备集成到药房系统中，将建立患者对其使用的信心，并最终导致更多的采用，从而提高服药依从性和健康结果，并降低医疗保健成本。

DESCRIPTION (provided by applicant): In this Phase II SBIR project, Concordance Health Solutions (CHS) will continue development of the ScanCap System and test its effectiveness on adherence rates and hypertension patient outcomes The ScanCap System is an electronic reminder cap that is seamlessly programmed at the pharmacy and incorporated into original packaging for prescription medications. The final product will also have the capability of recording when doses are taken and reporting that information back to caregivers and healthcare partners to improve patient medication adherence. The specific aims of the Phase II study are: Aim 1: Manufacture the ScanCap and complete development of the hardware and software to collect data stored on the device; Aim 2: Determine whether medication adherence can be improved through the use of the ScanCap compared with a placebo cap; and Aim 3: Determine whether BP control can be improved through use of the ScanCap compared with a placebo cap. Improving medication adherence is a current focus area of several NIH institutes and in line with the NIH mission to extend healthy life and reduce the burdens of illness and disability. The Scan Cap is designed to be manufactured for around $2/unit in high volumes and includes a wireless interface to automatically program the cap at the pharmacy; visual and audible reminders when a dose is due; and the ability to record doses taken and wirelessly transmit the patient medication record to an electronic database. It is small and easily portable with a design adaptable to standard prescription vials and safety cap features. Future features will include the ability to connect with a smart phone for real-time reminders. At the conclusion of Phase II, CHS will have manufactured the ScanCap electronic reminder cap and a prototype of the data collection system. CHS will also have demonstrated the effect of patients using the ScanCap system on medication adherence and blood pressure control. Proper adherence to prescription medication regimens is shown to improve overall health outcomes and reduce healthcare costs for many patients. However, typical medication adherence rates are less than 50 percent for a host of reasons that are both intentional in nature and unintentional, such as forgetfulness and confusion. Reminder devices on the market now are not available as part of the original prescription package, leaving the patient to sort through and implement over the counter reminder products on their own. An easy-to-use reminder cap that fits standard prescription vials will give pharmacists a tool to help their patients with medication dosing schedules. Integrating the reminder device into the pharmacy system will create patient confidence in its use and will ultimately result in increased adoption, leading to better medicatio adherence and health outcomes and lower healthcare costs. PUBLIC HEALTH RELEVANCE: Poor medication adherence has been described as a significant public health concern. It is widely recognized that non-compliance with medication dosing schedules limits success of treatment, contributes to disease complications, and increases hospitalizations and nursing home admissions, thereby increasing the cost of care for patients and payors. This research will study how a simple medication reminder device dispensed as part of the original prescription packaging can improve medication adherence rates in patients who use it.