Effect of ScanCap Technology on Medication Adherence and Hypertension Outcomes

描述(由申请人提供)：在这个第二阶段的SBIR项目中，Concorance Health Solutions(CHS)将继续开发ScanCap系统，并测试其对依从率和高血压患者结局的有效性。ScanCap系统是一种电子提醒帽，可在药房无缝编程，并整合到处方药的原始包装中。最终产品还将能够记录服用剂量的时间，并将这些信息报告给护理人员和医疗保健合作伙伴，以提高患者的服药依从性。第二阶段研究的具体目标是：目标1：制造ScanCap并完成硬件和软件的开发，以收集存储在设备上的数据；目标2：确定与安慰剂帽相比，使用ScanCap是否可以改善药物依从性；以及目标3：确定与安慰剂帽相比，使用ScanCap是否可以改善血压控制。改善服药依从性是几个NIH研究所目前的重点领域，符合NIH延长健康寿命和减少疾病和残疾负担的使命。Scan Cap的设计价格约为2美元/件，批量生产，它包括一个无线接口，可在药房自动对盖子进行编程；在剂量到期时发出视觉和声音提醒；以及记录所用剂量并将患者用药记录无线传输到电子数据库的能力。它体积小，便于携带，具有适合标准处方药瓶和安全帽功能的设计。未来的功能将包括与智能手机连接以进行实时提醒。在第二阶段结束时，CHS将制造出ScanCap电子提示帽和数据收集系统的原型。CHS还将展示患者使用ScanCap系统在服药依从性和血压控制方面的效果。研究表明，适当地遵循处方药疗法可以改善整体健康状况，并降低许多患者的医疗成本。然而，典型的服药依从率不到50%，原因有很多，既有刻意的，也有无意的，如健忘和困惑。市场上的提醒设备现在不能作为原始处方套餐的一部分提供，让患者自己挑选和实施柜台提醒产品。一个易于使用的提醒盖，适合标准的处方药瓶，将为药剂师提供一个工具，以帮助他们的患者的药物剂量计划。将提醒设备集成到药房系统中将建立患者对其使用的信心，最终将导致更多的人采用该设备，从而提高服药依从性和健康结果，并降低医疗成本。

DESCRIPTION (provided by applicant): In this Phase II SBIR project, Concordance Health Solutions (CHS) will continue development of the ScanCap System and test its effectiveness on adherence rates and hypertension patient outcomes The ScanCap System is an electronic reminder cap that is seamlessly programmed at the pharmacy and incorporated into original packaging for prescription medications. The final product will also have the capability of recording when doses are taken and reporting that information back to caregivers and healthcare partners to improve patient medication adherence. The specific aims of the Phase II study are: Aim 1: Manufacture the ScanCap and complete development of the hardware and software to collect data stored on the device; Aim 2: Determine whether medication adherence can be improved through the use of the ScanCap compared with a placebo cap; and Aim 3: Determine whether BP control can be improved through use of the ScanCap compared with a placebo cap. Improving medication adherence is a current focus area of several NIH institutes and in line with the NIH mission to extend healthy life and reduce the burdens of illness and disability. The Scan Cap is designed to be manufactured for around $2/unit in high volumes and includes a wireless interface to automatically program the cap at the pharmacy; visual and audible reminders when a dose is due; and the ability to record doses taken and wirelessly transmit the patient medication record to an electronic database. It is small and easily portable with a design adaptable to standard prescription vials and safety cap features. Future features will include the ability to connect with a smart phone for real-time reminders. At the conclusion of Phase II, CHS will have manufactured the ScanCap electronic reminder cap and a prototype of the data collection system. CHS will also have demonstrated the effect of patients using the ScanCap system on medication adherence and blood pressure control. Proper adherence to prescription medication regimens is shown to improve overall health outcomes and reduce healthcare costs for many patients. However, typical medication adherence rates are less than 50 percent for a host of reasons that are both intentional in nature and unintentional, such as forgetfulness and confusion. Reminder devices on the market now are not available as part of the original prescription package, leaving the patient to sort through and implement over the counter reminder products on their own. An easy-to-use reminder cap that fits standard prescription vials will give pharmacists a tool to help their patients with medication dosing schedules. Integrating the reminder device into the pharmacy system will create patient confidence in its use and will ultimately result in increased adoption, leading to better medicatio adherence and health outcomes and lower healthcare costs.