2013 Molecular and Cellular Biology of Lipids Gordon Research Conference

描述（由申请人提供）：本申请要求对2013年脂质分子和细胞生物学戈登研究会议（GRC）的部分支持，该会议汇集了脂质领域的领先科学家，介绍和讨论他们的研究，并促进研究进展。该Lipids GRC每隔一年举办一次，已近50年，是国际公认的脂质生物化学和分子生物学领域开创性和创新性研究的主要论坛。2013年，会议将重点关注脂质的持续出现，以了解参与肥胖、肝脂肪变性、心肌病、动脉粥样硬化和糖尿病等慢性疾病发展的潜在机制。创新包括选择a）新参加本次会议的发言者，B）以前没有受到关注的新颖主题，以及c）为初级和高级研究人员提供更多参与科学讨论的机会。新的主题包括自噬，G-偶联蛋白受体的配体是脂肪酸，硫酯酶代谢和功能，磷脂酸信号，和微RNA，全球调节脂质代谢。在2013年的另一项创新中，我们将留出特定的桌子，让初级参与者可以与演讲者共进午餐。会议将于7月17日至22日在新罕布什尔州沃特维尔山谷的沃特维尔山谷度假村举行，将包括9个讲座和4个下午的海报会议。讲座将涵盖广泛的主题，包括调节细胞代谢的脂质信号，脂肪酶和酰基转移酶的新作用，膜生物发生和营业额，细胞脂质代谢，脂肪酸代谢，脂质的转录控制，磷脂酸的聚光灯，以及通过microRNA对脂质的遗传调节。在这些会议中，超过35位演讲者将描述使用多种实验方法在一系列生物系统中进行的研究，包括人类，寄生虫，斑马鱼和酵母。在脂质GRC的分子和细胞生物学的会谈，以及大型和生动的海报会议，传统上激发与会者之间的激烈和动态的讨论，包括生物化学家，细胞生物学家，遗传学家，分子生物学家，结构生物学家，生理学家和医生。会议仅限200人参加，会议的亲密气氛使与会科学家能够密切互动。由此产生的讨论推动了该领域的未来进步和多学科合作。参与者和演讲者已经并将被选择，以反映这一医学相关科学领域的国际卓越，在年轻和经验之间取得理想的平衡。该计划包括杰出的女性和男性，以及不同种族的科学家。有设施可供残疾人使用。

DESCRIPTION (provided by applicant): This application requests partial support for the 2013 Molecular and Cellular Biology of Lipids Gordon Research Conference (GRC), a meeting that brings together leading scientists in the lipid field to present and discuss their research and to facilitate research advances. This Lipids GRC has been held every other year for almost 50 years and is internationally recognized as the major forum for the presentation of ground breaking and innovative research in lipid biochemistry and molecular biology. In 2013, the conference will focus heavily on the continuing emergence of lipids in understanding underlying mechanisms involved in the development of chronic diseases like obesity, hepatic steatosis, cardiomyopathy, atherosclerosis, and diabetes. Innovations include the selection of a) speakers who are new to this conference, b) novel topics that have not previously received attention, and c) enhanced opportunities for junior and senior investigators to engage in scientific discussion. New topics include autophagy, G-coupled protein receptors whose ligands are fatty acids, thioesterase metabolism and function, phosphatidate signaling, and microRNAs that globally regulate lipid metabolism. In another 2013 innovation, we will set aside specific tables where junior participants can meet the speakers for lunch. The meeting will be held July 17 - 22 at the Waterville Valley Resort in Waterville Valley, NH, and will include nine lecture sessions and four afternoon poster sessions. Lecture sessions will cover a broad range of topics, including Lipid signals that regulate cell metabolism, New roles for lipases and acyltransferases, Membrane biogenesis and turnover, Cellular lipid metabolism, Fatty acid metabolism, Transcriptional control of lipids, a Spotlight on phosphatidate, and the Genetic regulation of lipids via microRNAs. The >35 speakers in these sessions will describe research done in an array of biological systems, including humans, parasites, zebra-fish, and yeast, using multiple experimental approaches. The talks at the Molecular and Cellular Biology of Lipids GRC, as well as the large and lively poster sessions, traditionally stimulate intense and dynamic discussions among the attendees who include biochemists, cell biologists, geneticists, molecular biologists, structural biologists, physiologists, and physicians. The intimate atmosphere of the meeting, which is limited to 200 participants, enables attending scientists to interact closely with each other. The resulting discussions drive future advances and multidisciplinary collaborations in the field. Participants and speakers have been and will be chosen to reflect international excellence in this medically-relevant area of science, with an ideal balance between youth and experience. The program includes outstanding women and men, and scientists of different ethnicities. Facilities are available to accommodate handicapped individuals.