CVD Epidemiology Training Program in Behavior, the Environment and Global Health

这项提案将资助一个新的NHLBI CVD EPI行为、环境和全球培训计划 健康，目前在NHLBI培训中代表性不足的至关重要的科学学科。这 该计划将在哈佛大学丰富的学术环境中培训博士后和博士后实习生 公共卫生学院及其附属机构，汇聚优秀教师 导师提供集成的、跨学科的体验和协作互动， 课程包括核心课程和选修课程，非指导性的实践职业培训，个人候选人 培训计划和持续的计划评估。尖端的教学培训和指导将创造一个 新一代高技能和热情的调查人员研究行为和 心脏代谢性疾病的环境危险因素；阐明培养标准、基因组变异、 以及改变这些风险因素的生物学和社会学途径；以及理解和利用全套 流行病学、干预性、环境和政策工具，以设计、实施和评估 有效的个体化、社区化和政策性干预，以减少有害风险因素的影响，促进 扩大保护性行为和环境因素，减弱或扭转令人震惊的全球 心脏代谢性疾病的趋势。培训将包括现代方法和分析技术。 需要研究心脏代谢性疾病与行为的交叉，包括观察性 成年期、青春期和早期生活的流行病学和干预；环境，包括 空气和环境毒素、社会风险和物理(建筑)环境；以及全球健康， 包括观察流行病学、人口学、比较风险评估和控制 个人和社区层面的干预措施。这项训练计划将增加相当大的力量 以及NHLBI对理解行为和环境决定因素的承诺， 发达国家和发展中国家的心血管和代谢性疾病的预防措施和治疗 发展中国家。 相关性(请参阅说明)： 培训新一代调查人员，了解行为和环境风险因素 影响心血管和代谢性疾病，以及如何以经济高效和可持续的方式改变这些疾病 因素，是我们这个时代最重要的科学任务之一。这些都是全球性的挑战，因为正在发生变化 行为和环境风险在全球范围内迅速增加心血管和代谢性疾病 而广泛使用昂贵的与药物和设备相关的新疗法可能并不实用或成本效益高。

This proposal will fund a new NHLBI CVD Epi Training Program in Behavior, the Environment, and Global Health, critically important scientific disciplines that are currently under-represented in NHLBI training. This Program will train both pre- and post-doctoral trainees in the rich academic environment of the Harvard School of Public Health and affiliated institutions locally and worldwide, bringing together outstanding faculty Mentors to provide integrated and interdisciplinary experiences and collaborative interactions, specialized curriculum with core and elective coursework, nondidactic practical career training, individual candidate training plans, and ongoing Program evaluation. Cutting-edge didactic training and mentoring will create a new generation of highly skilled and enthusiastic investigators to study the impact of behavioral and environmental risk factors on cardiometabolic diseases; to elucidate the cultural norms, genomic variation, and biologic and sociologic pathways that modify these risk factors; and to understand and utilize the full set of epidemiologic, interventional, environmental, and policy tools to design, implement, and evaluate the most effective individualized, community, and policy interventions to reduce impact of harmful risk factors, facilitate expansion of protective behavioral and environmental factors, and attenuate or reverse the alarming global trends in cardiometabolic diseases. Training will include modern methodological and analytical techniques required to study the intersections of cardiometabolic diseases with Behavior, including observational epidemiology and interventions in adulthood, adolescence, and early life; the Environment, including airborne and environmental toxins, social risks, and physical (built) environment; and Global Health, including observational epidemiology, demography, comparative risk assessment, and controlled interventions at both individual and community levels. This Training Program will add considerable strength and depth to the NHLBI's commitment to understanding the behavioral and environmental determinants, preventive measures, and treatments of cardiovascular and metabolic diseases in both developed and developing nations. RELEVANCE (See instructions): Training a new generation of investigators to understand how behavioral and environmental risk factors impact cardiovascular and metabolic diseases, and how to cost-effectively and sustainably modify these factors, is among the most important scientific tasks of our time. These are global challenges, as changing behaviors and environmental risks are rapidly increasing cardiovascular and metabolic diseases worldwide and widespread use of costly new drug- and device-related treatments may not be practical or cost-effective.