Short Term Research Education Program to Increase Diversity in Health Research

短期研究教育计划，以增加健康研究的多样性

• 批准号: 8442862
• 负责人: Bertram Harold Lubin
• 金额: $ 16.37万
• 依托单位: CHILDREN'S HOSPITAL & RES CTR AT OAKLAND
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8442862
• 关键词: Area; Award; Basic Science; Biomedical Research; California; Cities; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Commit; Communities; County; Education; Educational Curriculum; Enrollment; Ensure; Exposure to; Fostering; Funding; Goals; Grant; Health; Health Occupations; Health Professional; Home environment; Laboratories; Los Angeles; Medical; Mentors; Mentorship; Minority; Mission; National Heart, Lung, and Blood Institute; Participant; Patients; Pediatric Hospitals; Population; Population Heterogeneity; Population Scientist Supplement (R25); Professional Role; Public Health; Qualifying; Recruitment Activity; Research; Research Activity; Research Institute; Research Personnel; Research Training; Resources; Role; San Francisco; Structure; Students; Training; Training and Education; Translational Research; Underrepresented Minority; United States National Institutes of Health; abstracting; arm; base; career; experience; graduate student; health disparity; interest; member; minority health; minority subjects; programs; role model; undergraduate research; undergraduate student; university student; volunteer

DESCRIPTION (provided by applicant): Children's Hospital Oakland Research Institute (CHORI), the research arm of Children's Hospital Oakland, is a premier medical and public health-related research organization in the eastern San Francisco Bay Area. Children's Hospital Oakland serves the surrounding counties, which are home to very diverse populations. CHORI is recognized internationally for its basic and clinical research. The clinical and laboratory based investigators at CHORI are committed to the goal of increasing diversity in health-related research and the health professions; research education and training of minorities are viewed as a key part of CHORI's effort to achieve this goal. For the past ten years, a NHLBI-funded summer minority undergraduate research program (T35) provided a structured curriculum and research training opportunity for 15 minority students at CHORI. Many college students also volunteer for this educational program, bringing the total number of students to 40 each summer. This year, on the advice of NHLBI, we are applying for this R25 award in lieu of seeking to renew our T35. The long-term goal of the CHORI Summer Research Program is to increase the number of underrepresented minorities in the basic and clinical sciences and provide opportunities to participate in research in NHLBI mission areas. The specific objectives of the current proposal are to: (1) Interest, encourage, and expose underrepresented undergraduate students and medical and health professional graduate students to career opportunities in basic, clinical and community-based biomedical research by offering short-term mentored research opportunities; (2) Stimulate students' interests and enhance exposure to minority health and health disparity issues; (3) Encourage past participants to continue to participate in the program to ensure their continued interest in pursuing careers in either basic or clinical research; (4) Inform students about the importance of increasing the number of minority subjects enrolled in clinical trials and the role of informed members of the community in increasing enrollments; (5) Pair each student with a mentor, who will provide a one-on-one mentorship and training in state-of-the-art research in a laboratory or clinical setting; (6) Provide culturally sensitive professional role models; (7) Develop and foster partnerships and sustained relationships with organizations at the regional and national level to ensure that we achieve these goals. Towards accomplishing these objectives, we will recruit 20 undergraduate and medical/health professional students each year for the next five years. We will provide short-term exposure to clinical and basic research activities of relevance to the mission of NHLBI for a 9-week period between June and August. The students will be recruited both from local areas and from across the nation, targeting areas that have documented large numbers of underrepresented populations. The CHORI Summer Research Program offers outstanding resources to students interested in clinical, basic and translational research at CHORI. Our experience in one-on-one mentoring of undergraduates and medical/health professional students, the commitment of our basic and clinical researchers to this education program, and our track record of successfully recruiting, training, and motivating students from underrepresented populations make CHORI well-qualified to receive this award. There is abundance evidence of the need for broader inclusion of underrepresented minorities in biomedical research and the health professions, both for recruiting subjects for clinical trials and treating patients. The Summer Research program at CHORI will aid efforts to encourage students from these populations to pursue careers in these fields. (End of Abstract)

描述（由申请人提供）：儿童医院奥克兰研究所（CHORI），儿童医院奥克兰的研究部门，是一个首屈一指的医疗和公共卫生相关的研究组织在东部旧金山弗朗西斯科湾区。奥克兰儿童医院为周围的县提供服务，这些县是非常多样化的人口的家园。CHORI因其基础和临床研究而获得国际认可。CHORI的临床和实验室研究人员致力于增加与健康有关的研究和卫生专业的多样性的目标;研究教育和少数民族的培训被视为CHORI努力实现这一目标的关键部分。在过去的十年中，NHLBI资助的夏季少数民族本科生研究计划（T35）为15名少数民族学生提供了结构化的课程和研究培训机会。许多大学生也自愿参加这个教育项目，使每年夏天的学生总数达到40人。今年，在NHLBI的建议下，我们申请了这个R25奖项，而不是寻求更新我们的T35。CHORI夏季研究计划的长期目标是增加基础和临床科学中代表性不足的少数民族的数量，并提供参与NHLBI使命领域研究的机会。目前提案的具体目标是：（1）通过提供短期指导研究机会，使代表性不足的本科生和医学和卫生专业研究生对基础、临床和社区生物医学研究的职业机会感兴趣，并鼓励他们这样做;（2）激发学生的兴趣，加强对少数群体健康和健康差距问题的了解;（3）鼓励过去的参与者继续参与该计划，以确保他们继续对从事基础或临床研究的职业感兴趣;（4）告知学生增加少数民族受试者参加临床试验的数量的重要性，以及社区知情成员在增加入学人数方面的作用;（5）为每名学生安排一名导师，导师将在实验室或临床环境中提供一对一的指导和最新研究培训;（七）发展和促进与区域和国家一级组织的伙伴关系和持续关系，以确保我们实现这些目标。为达致这些目标，我们会在未来五年，每年招收20名本科生及医学/健康专业学生。我们将在6月至8月期间提供为期9周的与NHLBI使命相关的临床和基础研究活动的短期接触。这些学生将从当地和全国各地招募，目标是记录了大量代表性不足的人口的地区。CHORI暑期研究计划为对CHORI的临床，基础和转化研究感兴趣的学生提供优秀的资源。我们在本科生和医学/健康专业学生的一对一指导经验，我们的基础和临床研究人员对这个教育计划的承诺，以及我们成功招募，培训和激励学生的记录来自代表性不足的人群，使CHORI很有资格获得这个奖项。 有大量证据表明，在生物医学研究和卫生专业中，无论是在招募临床试验对象还是在治疗病人方面，都需要更广泛地吸收代表性不足的少数群体。在CHORI的夏季研究计划将有助于努力鼓励来自这些人群的学生在这些领域从事职业。 (End摘要）

项目成果

Orange juice limits postprandial fat oxidation after breakfast in normal-weight adolescents and adults.

橙汁可以限制正常体重的青少年和成人早餐后的餐后脂肪氧化。

• DOI: 10.3945/an.112.001990
• 发表时间: 2012
• 期刊: Advances in nutrition (Bethesda, Md.)
• 作者: Stookey,JodiDunmeyer;Hamer,Janice;Espinoza,Gracie;Higa,Annie;Ng,Vivian;Tinajero-Deck,Lydia;Havel,PeterJ;King,JanetC
• 通讯作者: King,JanetC

Intrathecal baclofen therapy after liver transplant in a patient with Crigler-Najjar syndrome.

克里格勒-纳贾尔综合征患者肝移植后鞘内注射巴氯芬治疗。

• DOI: 10.1016/j.pmrj.2013.09.004
• 发表时间: 2014
• 期刊: PM & R : the journal of injury, function, and rehabilitation
• 作者: Pratini,NapalaR;Neufeld,JacobA
• 通讯作者: Neufeld,JacobA

Pyrene: a probe to study protein conformation and conformational changes.

• DOI: 10.3390/molecules16097909
• 发表时间: 2011-09-14
• 期刊: Molecules (Basel, Switzerland)
• 作者: Bains G;Patel AB;Narayanaswami V
• 通讯作者: Narayanaswami V

Qualitative and/or quantitative drinking water recommendations for pediatric obesity treatment.

用于儿童肥胖治疗的定性和/或定量饮用水建议。

• DOI: 10.4172/2165-7904.1000232
• 发表时间: 2014
• 期刊: Journal of obesity & weight loss therapy
• 作者: Stookey,JodiD;DelToro,Rigoberto;Hamer,Janice;Medina,Alma;Higa,Annie;Ng,Vivian;TinajeroDeck,Lydia;Juarez,Lourdes
• 通讯作者: Juarez,Lourdes

Treatment of classic pantothenate kinase-associated neurodegeneration with deferiprone and intrathecal baclofen.

用去铁酮和鞘内注射巴氯芬治疗经典的泛酸激酶相关神经变性。

• DOI: 10.1097/phm.0b013e318282d209
• 发表时间: 2013
• 期刊: American journal of physical medicine & rehabilitation
• 影响因子: 3
• 作者: Pratini,NapalaR;Sweeters,Nancy;Vichinsky,Elliott;Neufeld,JacobA
• 通讯作者: Neufeld,JacobA