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Administrative Core

Administrative Core
行政核心
批准号：
8460256
负责人：
Ira A Tabas
金额：
$16.35万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
未结题
起止时间：
2007-07-15 至
来源：
https://reporter.nih.gov/project-details/8460256
关键词：
ApoptosisArterial Fatty StreakAtherosclerosisBiological AssayBiostatistics CoreCell AdhesionCellsEnsureExperimental DesignsGene ExpressionIn SituInflammationInsulin ResistanceLesionManuscriptsServicesatherogenesisdesignexperimental analysislaser capture microdissection

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中文摘要
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英文摘要
The Lesion Analysis/ Biostatistics Core has been widely used by each of the three projects in the design and assessment of atherosclerosis studies (refs 1-6, and submitted manuscripts described within specific projects). The Core ensures consistent quantitative and qualitative assessment of atherosclerotic lesions, adequately powered experimental design and appropriate analysis of experimental results. Specific services include A) quantification of atherosclerotic lesions; B) qualitative assessment of lesion composition; C) apoptosis and in situ efferocytosis assays; D) markers of cell adhesion and inflammation; E) laser-capture microdissection (LCM) for cell-specific quantitative gene expression analyses; and F) biostatisticai support including power calculations.
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A Mechanistic and Translational Research Program Linking Impaired Resolution, Defective Efferocytosis, and Clonal Hematopoiesis to the Formation of Clinically Dangerous Atherosclerotic Plaques
A Mechanistic and Translational Research Program Linking Impaired Resolution, Defective Efferocytosis, and Clonal Hematopoiesis to the Formation of Clinically Dangerous Atherosclerotic Plaques
A Mechanistic and Translational Research Program Linking Impaired Resolution, Defective Efferocytosis, and Clonal Hematopoiesis to the Formation of Clinically Dangerous Atherosclerotic Plaques
A Mechanistic and Translational Research Program Linking Impaired Resolution, Defective Efferocytosis, and Clonal Hematopoiesis to the Formation of Clinically Dangerous Atherosclerotic Plaques