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中文摘要
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描述(由申请人提供):本提案请求资助2014年戈登细胞死亡研究会议,会议将于2014年6月8日至13日在美国佛蒙特州西多佛的雪山度假村举行。细胞死亡戈登会议是细胞死亡界最受重视的国际会议之一。参加者将作口头报告、主持讨论或以海报形式展示他们的作品。为了与戈登会议的亲密精神保持一致,出席人数将受到限制,并且演讲将包括该领域前沿的未发表的作品。本次会议的总体目标是加快细胞死亡研究的进展,并利用研究成果开发新的治疗方法。第二个目标是促进细胞死亡研究人员和研究人员在互补的基础、转化和临床领域的合作。本次会议的目的是:1)在一个支持结构化和随意互动的环境中,将成熟的专家与该领域的初级科学家和研究人员聚集在一起;2)促进与细胞死亡在健康、衰老和病理背景下的作用相关的前沿、创新和未发表的科学的交流;3)加快发现,推进细胞死亡的机制知识,促进临床机会,治疗和诊断由这一过程的错误调节引起的疾病。会议的主要主题将集中在:1)细胞信号,生存和死亡,2)线粒体,代谢和细胞死亡,3)凋亡网络,4)死亡细胞的清除,5)非凋亡死亡途径,6)细胞生存,死亡和癌症,7)细胞生存,死亡和神经系统。会议将促进最近的突破性发现与癌症、免疫紊乱和神经退行性疾病的新疗法的发展相结合。
英文摘要
DESCRIPTION (provided by applicant): This proposal requests funds to help support the 2014 Gordon Research Conference on Cell Death to be held from June 8 - 13, 2014 at Mount Snow Resort in West Dover, Vermont, USA. The Cell Death Gordon Conference is among the most highly regarded international conferences in the cell death community. Participants will give oral presentations, lead discussions or present their work in poster format. In keeping with the intimate spirit of the Gordon Conference, attendance will be limited, and presentations will include unpublished work at leading edge of this field. The overall goal of this conference is to expedite progress in cell death research and to use research findings for the development of new therapies. A secondary goal is to facilitate collaborations among cell death researchers and investigators in complementary basic, translational and clinical fields. The aims of this conference are to: 1) gather established experts together with junior scientists and researchers new to this field in a setting that supports structured and casual interactions, 2) promote exchange of cutting edge, innovative and unpublished science relevant to the roles of cell death in healthy, aging and pathologic contexts, 3) Expedite discoveries that advance mechanistic knowledge on cell death and facilitate clinical opportunities for the treatment and diagnosis of diseases caused by the mis- regulation of this process. The major themes of the meeting will focus on: 1) cell signaling, survival and death, 2) mitochondria, metabolism and cell death, 3) apoptotic networks, 4) clearance of dying cells, 5) non-apoptotic death pathways, 6) cell survival, death and cancer, and 7) cell survival, death and the nervous system. The meeting will facilitate the alignment of recent breakthrough discoveries with the development of new therapies for cancer, immunological disorders and neurodegenerative diseases.
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