Training Program in the Pathophysiology of Renal Disease

描述（由申请人提供）：建议在内科住院医师项目或博士项目后招募博士后医学博士，继续进行肾脏疾病病理生理学的机构培训计划。该培训计划的目标是在肾脏研究的四个领域培养医生和博士科学家，包括i)急性肾损伤，ii)慢性肾脏疾病的心血管风险，iii)肾移植的基础科学方面和iv)糖尿病肾病的新疗法。这些领域将提供基础和临床转化研究方面的综合培训。该培训计划将要求由T32拨款资助的两年研究承诺，然后是一年的医学博士临床培训。在第一年，学员将可以选择参加课程，通过跨学科生物医学科学（IBS）研究生课程获得临床和转化科学证书。该项目师资队伍来自肾脏科、药理学与毒理学、微生物学与免疫学、生物化学与分子生物学、老年病学、生理学与生物物理学等部门，包括9名医学博士、3名医学博士、11名博士和1名医学硕士。学员应掌握至少一项主要调查技术，完成至少一项重大研究项目，在国家会议上展示他们的工作，并在研究培训结束时申请NIH资助（K08奖）。完成该项目的研究员将成为学术研究事业的竞争候选人。

DESCRIPTION (provided by applicant): Continuation of an institutional Training Program in the Pathophysiology of Renal Diseases is proposed for postdoctoral MDs recruited after internal medicine residency program or PhDs. The goals of this training program are to train physicians and PhD scientists in four areas of renal research including i) acute kidney injury, ii) cardiovascular risk of chronic kidney disease, iii) basic science aspects of renal transplantation and iv) new therapies for diabetic nephropathy. These areas will provide comprehensive training in basic and clinical translational research. The training program will require a commitment of two years of research funded by the T32 grant followed by one year of clinical training for MDs. During the first year the trainees will have the option to enroll in coursework to earn a Certificae in Clinical and Translational Sciences through the Interdisciplinary Biomedical Sciences (IBS) Graduate Program. The program faculty represents a closely-knit, interactive, multidisciplinary faculty from the Division of Nephrology and Departments of Pharmacology and Toxicology, Microbiology and Immunology, Biochemistry and Molecular Biology, Geriatrics, and Physiology and Biophysics including 9 MDs, 3 MD PhDs, 11 PhDs, and 1 MD MPH. Trainees are expected to master at least one major investigative technique, complete at least one major research project, present their work at a national meeting and apply for NIH funding (K08 award) at the end of their research training. Fellows completing this program will be competitive candidates for academic research careers.