Mayo Clinic Research Education Program in Computational Autonomic Neurobiology of Diabetes and Digestive and Kidney Diseases

梅奥诊所糖尿病、消化和肾脏疾病计算自主神经生物学研究教育项目

基本信息

  • 批准号:
    10709578
  • 负责人:
  • 金额:
    $ 12.96万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-09-30 至 2027-06-30
  • 项目状态:
    未结题

项目摘要

Project Summary / Abstract Modern biomedical science and medicine, with large varied and complex datasets, requires a paradigm shift in our educational models to train the next generation of scientists and physicians capable of performing and interpreting computational analyses. Current educational models have created a critical gap of expertise between computational data scientists and disease-oriented physiologists. The Specific Aim of this proposal is to establish an innovative educational model to promote the training of computational skills for immediate and direct application to research experiences and create the next generation of biomedical scientists to lead new discoveries in diabetes, digestive and kidney disease-oriented research. The Mayo Clinic Research Education Program in Computational Autonomic Neurobiology is a unique new program designed to ensure foundational understanding of both computational science and disease-oriented physiology, prior to learning practical skills in computational methods that are directly applied to data from mentored research experiences. Participants in the program, including graduate students, post-doctoral fellows, biomedical engineers, medical residents, and clinical fellows, are recruited widely from existing educational, training and research programs via the international reputations and productivity of the highly invested participating faculty. The program leverages institutional resources for program administration and robust program evaluation to remain adaptive and responsive to the needs of participants. The short-term objectives of the program are to: 1) provide foundational knowledge in physiology and computational science; 2) provide practical skill in the use creation and dissemination of computational workflows; and 3) provide a research environment to enrich skill honing and productivity. The long-term objectives of the program are to: 4) expand the use and access of computational analyses to impact diabetes, digestive and kidney disease-oriented research; and 5) attract and retain diverse scientists that impact the fields of diabetes, digestive and kidney disease- oriented research. By completing the program, we anticipate these scientists will form a bridge between the often distant physiological and computational approaches to understand human health and form a generation of diverse scientists that impact the fields of diabetes, digestive and kidney diseases.
项目摘要/摘要

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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David R. Linden其他文献

Su1212 THE ELECTROGENIC SODIUM/BICARBONATE COTRANSPORTER SLC4A4 IS REQUIRED FOR SLOW WAVE (SW) GENERATION BY INTERSTITIAL CELLS OF CAJAL (ICC) BUT IS NOT SOLELY RESPONSIBLE FOR THE EFFECTS OF BICARBONATE ON SW ACTIVITY
  • DOI:
    10.1016/s0016-5085(24)02067-5
  • 发表时间:
    2024-05-18
  • 期刊:
  • 影响因子:
  • 作者:
    Natalie R. Wertish;Peter R. Strege;Siva Arumugam Saravanaperumal;Cheryl Bernard;Gianluca Cipriani;David R. Linden;Linda C. Hsi;Michael F. Romero;Gianrico Farrugia;Tamas Ordog
  • 通讯作者:
    Tamas Ordog
Su1236 TRP53-MEDIATED CELL CYCLE ARREST OF PRECURSORS RATHER THAN CELLULAR SENESCENCE UNDERLIES INTERSTITIAL CELL OF CAJAL DEPLETION DURING AGING
  • DOI:
    10.1016/s0016-5085(20)32084-9
  • 发表时间:
    2020-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    Yujiro Hayashi;David R. Linden;Siva Arumugam Saravanaperumal;Yoshitaka Toyomasu;Simon J. Gibbons;Huihuang Yan;Gianrico Farrugia;Tamas Ordog
  • 通讯作者:
    Tamas Ordog
111 Altered P<sub>2</sub>X<sub>3</sub> Receptors in Prevertebral Ganglia During Colitis Is Dependent on Mammalian Target of Rapamycin
  • DOI:
    10.1016/s0016-5085(13)60091-8
  • 发表时间:
    2013-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    David R. Linden
  • 通讯作者:
    David R. Linden
561 OPTOGENETIC STIMULATION OF INTESTINAL ENTEROENDOCRINE CELLS CAUSES EPITHELIAL CHLORIDE SECRETION THROUGH NEUROGENIC AND PARACRINE MECHANISMS
  • DOI:
    10.1016/s0016-5085(23)01202-7
  • 发表时间:
    2023-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    Aura S. Ortegon Nino;Kaitlyn R. Knutson;Xi Yu;Halil S. Kacmaz;Anthony J. Treichel;Gianrico Farrugia;Arthur Beyder;David R. Linden
  • 通讯作者:
    David R. Linden
671 MECHANOSENSITIVE ENTEROENDOCRINE CELLS REGULATE FORCE-INDUCED EPITHELIAL SECRETION
  • DOI:
    10.1016/s0016-5085(21)01065-9
  • 发表时间:
    2021-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    Isabelle W. Finholm;Anthony J. Treichel;Kaitlyn R. Knutson;Madhusudan Grover;David R. Linden;Andrew B. Leiter;Gianrico Farrugia;Arthur Beyder
  • 通讯作者:
    Arthur Beyder

David R. Linden的其他文献

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{{ truncateString('David R. Linden', 18)}}的其他基金

Neurobiology of Intrinsic Primary Afferent Neurons
内在初级传入神经元的神经生物学
  • 批准号:
    10477437
  • 财政年份:
    2021
  • 资助金额:
    $ 12.96万
  • 项目类别:
Neurobiology of Intrinsic Primary Afferent Neurons
内在初级传入神经元的神经生物学
  • 批准号:
    10680037
  • 财政年份:
    2021
  • 资助金额:
    $ 12.96万
  • 项目类别:
Neurobiology of Intrinsic Primary Afferent Neurons
内在初级传入神经元的神经生物学
  • 批准号:
    10654779
  • 财政年份:
    2021
  • 资助金额:
    $ 12.96万
  • 项目类别:
Neurobiology of Intrinsic Primary Afferent Neurons
内在初级传入神经元的神经生物学
  • 批准号:
    10275133
  • 财政年份:
    2021
  • 资助金额:
    $ 12.96万
  • 项目类别:
Neuroregeneration in the Enteric Nervous System
肠神经系统的神经再生
  • 批准号:
    8937180
  • 财政年份:
    2015
  • 资助金额:
    $ 12.96万
  • 项目类别:
Little Brain Big Brain Meeting
小脑大脑会议
  • 批准号:
    7745365
  • 财政年份:
    2009
  • 资助金额:
    $ 12.96万
  • 项目类别:
Extrinsic Neural Control of Gastrointestinal Function in the Disordered Bowel
肠道紊乱胃肠功能的外在神经控制
  • 批准号:
    8033223
  • 财政年份:
    2008
  • 资助金额:
    $ 12.96万
  • 项目类别:
Extrinsic Neural Control of Gastrointestinal Function in the Disordered Bowel
肠道紊乱胃肠功能的外在神经控制
  • 批准号:
    8217087
  • 财政年份:
    2008
  • 资助金额:
    $ 12.96万
  • 项目类别:
Extrinsic Neural Control of Gastrointestinal Function in the Disordered Bowel
肠道紊乱胃肠功能的外在神经控制
  • 批准号:
    7595197
  • 财政年份:
    2008
  • 资助金额:
    $ 12.96万
  • 项目类别:
Myenteric Neuroplasticity Due to Experimental Colitis
实验性结肠炎引起的肌间神经可塑性
  • 批准号:
    6524630
  • 财政年份:
    2002
  • 资助金额:
    $ 12.96万
  • 项目类别:

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    2243108
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