Academic Training in Hematology

血液学学术培训

• 批准号: 8701337
• 负责人: John P Chute
• 金额: $ 27.01万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8701337
• 关键词: Academic Training; Hematology

DESCRIPTION (provided by applicant): This is a resubmission of a competitive renewal application for a PHS Institutional National Service Award (T32 HL66992) at the David Geffen School of Medicine at UCLA to prepare post-doctoral fellows for an academic career in Hematology. This award was initiated in July, 2002, and supports 4 fellowship slots in years 2 and 3 of Hematology/Medical Oncology training. The Program Director is Victor Marder, MD, and the Associate Program Director is Donald Kohn, MD. In keeping with the NHLBI mission for training fellows in non-malignant hematology, we have made significant changes in our program regarding leadership, research foci, and selection of and funding of fellows for their research years of training. Of note are 1) the appointment of a pediatric hematology fellow who will study gene transplantation in sickle cell disease, 2) the elimination of an existing research focus in Leukemia, and 3) re-organization of Training Grant leadership to reflect our focus on non-malignant hematology. Since 2002, 22 fellows have completed their fellowship at UCLA, 15 of which (68%) are actively involved in research, 12 (55%) as full-time faculty at a University or Medical Center or in a full-time research position in industry, and 3 with active clinical research programs as part of their practice, including 2 who have voluntary university appointments. In the last 3 years (2010-2012), 7 of 8 graduates (87.5%) entered full- or part-time university or industry positions of research. All fellows entering the program are Training Grant Eligible (TGE). The faculty consists of 31 academic scientists and physicians, 89% of whom have NIH grant funding, grouped into 3 research foci, Hematopoiesis and Stem Cell Biology (Don Kohn, MD, Director), Lymphocyte Biology (John Timmerman, MD, Director) and Coagulation and Vascular Biology (Victor Marder, MD, Director). Interaction with other training programs in complementary disciplines, notably those in the Broad Stem Cell Research Center, the T32 Training Grant in Developmental Hematology, and the NCI T32 Training Grant in Medical Oncology, emphasizes the resources available to meet our mission of basic and translational research careers. A core curriculum is offered to all fellows, including a "Clinical Research Course", which covers subjects on research design and analysis, ethics, regulatory issues, grant preparation and responsible conduct of research. Fellows are encouraged to obtain an advanced degree as part of the STAR program, and 2 have obtained the Master's degree and 2 a PhD degree. Formal review of the mentor's effectiveness and the fellow's achievements are prepared by the Steering Committee, made up of the 3 Focus Directors, the PI of the Division Oncology Training Grant (Antoni Ribas, MD, PhD), and the Director of the Division Fellowship Training Program (Arash Naeim, MD, PhD). Three research retreats are held each year, fall retreats at which first year research proposals are proposed and second year progress reports are reviewed, and a spring retreat for final reports of graduating fellows. We are proud of our success in training underrepresented Minority candidates, 3 of 13 (23%) since 2007 being Hispanic or African-American.

描述（由申请人提供）：这是重新提交的竞争性更新申请的PHS机构国家服务奖（T32 HL 66992）在大卫格芬医学院在加州大学洛杉矶分校准备博士后研究员在血液学的学术生涯。该奖项于2002年7月启动，支持血液学/内科肿瘤学培训第2年和第3年的4个奖学金名额。项目主任是医学博士维克托马德尔，副项目主任是医学博士唐纳德科恩。为了与NHLBI在非恶性血液学方面培训研究员的使命保持一致，我们在我们的项目中对领导力、研究重点以及研究员的选择和资助进行了重大改变。值得注意的是1）任命一名儿科血液学研究员，他将研究镰状细胞病的基因移植，2）消除现有的白血病研究重点，3）重新组织培训补助金领导，以反映我们对非恶性血液学的关注。自2002年以来，已有22名研究员完成了在加州大学洛杉矶分校的研究，其中15名（68%）积极参与研究，12名（55%）在大学或医学中心担任全职教师或在工业界担任全职研究职位，3名从事积极的临床研究 项目作为他们实践的一部分，包括2谁有自愿大学任命。在过去的3年（2010-2012年），8名毕业生中有7名（87.5%）进入全职或兼职大学或行业研究职位。所有进入该计划的研究员都有资格获得培训补助金（TGE）。该学院由31名学术科学家和医生组成，其中89%拥有NIH拨款资助，分为3个研究重点，造血和干细胞生物学（Don Kohn，MD，主任），淋巴细胞生物学（John Timmerman，MD，主任）和凝血和血管生物学（维克托Marder，MD，主任）。与互补学科的其他培训计划的互动，特别是那些在广泛的干细胞研究中心，在发育血液学的T32培训补助金，和NCI T32培训补助金在医学肿瘤学，强调可用的资源，以满足我们的基础和转化研究事业的使命。向所有研究员提供核心课程，包括“临床研究课程”，内容涉及研究设计和分析、伦理、管理问题、赠款准备和负责任地开展研究。鼓励研究员获得高级学位作为星星计划的一部分，2人获得硕士学位，2人获得博士学位。指导委员会负责对导师的有效性和研究员的成就进行正式审查，指导委员会由3名焦点主任、肿瘤学培训补助金部门的PI（Antoni Ribas，MD，PhD）和研究员培训计划部门的主任（Arash Naeim，MD，PhD）组成。每年举行三次研究务虚会，秋季务虚会提出第一年的研究建议，并审查第二年的进展报告，春季务虚会为毕业研究员的最后报告。我们为我们在培训代表性不足的少数民族候选人方面取得的成功感到自豪，自2007年以来，13人中有3人（23%）是西班牙裔或非洲裔美国人。