ADVANCING LOCOMOTION AND DEVELOPMENT IN YOUNG CHILDREN WITH DOWN SYNDROME

促进患有唐氏综合症的幼儿的运动和发育

• 批准号: 8622489
• 负责人: JAMES C. GALLOWAY
• 金额: $ 22.19万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-09 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8622489
• 关键词: Address; Automobile Driving; Behavioral; Biomechanics; Brain; Categories; Child; Childhood; Clinical; Clinical Research; Code; Cognitive; Data; Development; Developmental Delay Disorders; Device Designs; Devices; Dose; Down Syndrome; Emotional; Environment; Equilibrium; Exercise; Family; Feasibility Studies; Funding; Funding Agency; Goals; Gold; Hour; Impairment; Industry; Infant; Infant Development; Intervention; Intervention Studies; Laboratories; Language; Language Development; Learning; Life; Locomotion; Measures; Mechanics; Modeling; Modification; Motion; Motor; Population; Positioning Attribute; Rehabilitation therapy; Research; Robot; Robotics; Role; Self-Help Devices; Series; Socialization; Technology; Testing; Therapeutic; Time; Toy; Training; United States National Institutes of Health; Walking; Wit; Work; assistive device/technology; clinically significant; cost; design; experience; follow-up; innovation; interest; novel; peer; programs; public health relevance; research and development; skills; skills training; social

PROJECT SUMMARY/ABSTRACT The overall goal of this clinical research program is to provide infants with Down syndrome (DS) with the training and technology to independently explore their world to the same degree as their typically developing peers. Moving and mobility comprise up to 80% of a young child's waking hours. Such a high dose of sitting, standing and walking are a lofty gold standard for pediatric rehabilitation. Down syndrome (DS), which delays sitting, standing and walking by up to a year, significantly reduces infants' daily exploration with serious cognitive, language, and social consequences. This proposal specifically tests the feasibility and effects of a novel 'mobile therapy environment' that provides powered mobility, progressive exercise and functional skills training in one assistive technology device. Our modified ride on cars specifically combine the fun and exploration of powered mobility (such as a Segway) with the ability to advance balance, strength and coordination through therapeutic exercises while infants practice sitting, standing and walking. Over the last year, we have developed a series of electrical and mechanical modifications that allow a single car to be progressively driven in sitting, then safely driven as triggered by standing (Figure 1 upper) then triggered by over ground walking (Figure 1 lower). This proposal will allow us to determine the feasibility and effect of ride on car training on sitting, standing and walking delays (Aim 1) and on infants' broader cognitive, language and social-emotional development (Aim 2). This proposal, inspired by our mobile robotics work and supported by preliminary data, is scientifically principled, innovative yet feasible within the funding period. The data and devices from this 2 yr project will support more formal work on the clinical and commercial potential of a novel category of assistive technology: the 'mobile therapy environment'. Figure 1 Modified ride on toy cars provide inexpensive effective mobility and socialization as well as strengthening, balance, coordination during driving while standing (Upper) and driving while walking (Lower).

项目总结/摘要 这项临床研究计划的总体目标是为婴儿提供 唐氏综合症（DS）的训练和技术，以独立探索他们的 与他们通常发展中的同龄人一样。移动和流动性 占幼儿清醒时间的80%如此高剂量的坐着，站着 和行走是儿科康复的黄金标准。唐氏综合征（DS）， 这会使坐、站和走路的时间推迟一年， 具有严重认知、语言和社会后果的探索。这项建议 专门测试了一种新型“移动的治疗环境”的可行性和效果， 提供动力移动，渐进式运动和功能技能培训在一个辅助 技术设备。 我们改装的汽车特别联合收割机结合的乐趣和探索动力流动 (such作为一个赛格威）的能力，以提高平衡，力量和协调， 治疗练习，而婴儿练习坐，站和走。在过去的一年里， 我们开发了一系列的电气和机械改造， 在坐姿时逐渐驾驶，然后在站立时安全驾驶（图1 上图），然后通过地面行走触发（图1下图）。 这项建议将使我们能够确定乘坐汽车培训的可行性和效果， 坐立和行走延迟（目标1）以及婴儿更广泛的认知、语言和 社会情感发展（目标2）。这个提议，灵感来自我们的移动的机器人工作 并得到初步数据的支持，是科学的原则，创新，但可行的范围内 融资期。来自这个2年项目的数据和设备将支持更正式的工作， 一种新型辅助技术的临床和商业潜力：“移动的” 治疗环境”。 图1改装后的骑乘装置 玩具汽车提供 廉价有效 流动性和社会化 以及加强， 平衡，协调 在行驶过程中， 站立（上）和 边走边开车 （下）。