Telluride Epithelial Physiology and Cell Biology Workshop

描述(由申请人提供)：上皮生理学和细胞生物学研讨会汇集了在上皮细胞转运和离子通道/转运体的细胞信号调节方面具有不同专业知识的研究人员与专注于疾病过程的临床医生，如前几届会议的成功所证明的那样，促进了合作和催化科学进步。该研讨会每年(自2004年以来)在科罗拉多州的特鲁里德举行，由特鲁里德科学研究中心提供后勤会议支持。演讲主题的前沿性体现在共同组织者约翰·库波莱蒂博士、我的N·赫尔姆斯、托马斯·克利曼、彼得·斯奈德和不同的演讲者身上。主题将包括(但不限于)自由基在离子传输中的作用，基于酸敏离子通道的X射线晶体结构的钠通道的分子建模，以及基于前列腺素化合物靶向氯离子通道的潜在用途。还将通过拟议的研究表彰旅行奖来加强初级研究人员对这次研讨会的参与。

DESCRIPTION (provided by applicant): Bringing together investigators with varied expertise in epithelial transport and cell signaling regulation of ion channels/transporters with clinicians focused on disease process, the Epithelial Physiology and Cell biology Workshop stimulates collaborations and catalyzes scientific progress, as has been exemplified by the successes of the previous meetings. This workshop is held annually (since 2004) in Telluride, Colorado with logistical meeting support provided by the Telluride Science Research Center. The cutting edge nature of topics to be presented is reflected in the co-organizers involved, Drs. John Cuppoletti, My N. Helms, Thomas Kleyman, Peter Snyder, and a diverse range of speakers. Topics will include (but is not limited to) the role of free radicals in ion transport, molecular modeling of sodium channels based on the X-ray crystal structure of acid sensing ion channels, and the potential use of prostone based compounds to target chloride channels. Participation by junior researchers in this workshop will also be enhanced through a proposed Research Recognition Travel Award.