Interactions Between Hedgehog and Ras Signaling in Lung Adenocarcinoma

肺癌是一种常见和致命的疾病在我们的社会。在这个项目中，我们探讨了调节胚胎肺发育的信号通路如何促进肺癌的发生和发展。为了做到这一点，我们使用了一个小鼠肺癌模型，在这个模型中，我们可以激活成年小鼠的胚胎信号通路来研究它们对疾病的影响。了解这些途径将有助于我们更好地治疗和预防人类肺癌。

Lung cancer is a common and lethal disease in our community. In this project, we explore how signaling pathways that regulate the development of the lung in embryos contribute to the initation and progression of lung cancer. To do this, we use a mouse model of lung cancer in which we can activate embryonic signaling pathways in adult mice to study there effect on the disease. Understanding these pathways will help us to better treat and prevent lung cancer in humans.