An in-vivo model of acquired chemoresistance in small cell lung cancer

小细胞肺癌获得性化疗耐药的体内模型

• 批准号: nhmrc : 546204
• 负责人: Prof David Watkins
• 金额: $ 24.26万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/an-in-vivo-lung-cancer/101433
• 关键词: vivo; model; acquired; chemoresistance; small

Lung cancer is a common and lethal disease in our community. In this project, we explore how a very aggressive form of lung cancer becomes resistant to chemotherapy. To do this, we use a new mouse model of lung cancer in which we can study how human lung cancer cells develop resistance to chemotherapy in vivo. Understanding these pathways will help us to better treat lung cancer with chemotherapy.

肺癌是一种常见和致命的疾病在我们的社会。在这个项目中，我们探索了一种非常侵袭性的肺癌如何对化疗产生耐药性。为了做到这一点，我们使用了一种新的肺癌小鼠模型，在这种模型中，我们可以研究人类肺癌细胞如何在体内对化疗产生耐药性。了解这些途径将有助于我们更好地用化疗治疗肺癌。