Interactions between IL-15 and TGF-beta signalling pathways reveal novel therapeutic strategies to boost anti-cancer immunity
Interactions between IL-15 and TGF-beta signalling pathways reveal novel therapeutic strategies to boost anti-cancer immunity
IL-15 和 TGF-β 信号通路之间的相互作用揭示了增强抗癌免疫的新治疗策略
批准号：
nhmrc : 1140406
负责人：
金额：
$30.05万
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2018
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2018-01-01 至 2020-12-31
中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
This project will determine if new immune inhibitory checkpoints can be synergistically targeted with BRAFV600E inhibition to reactivate and allow NK cells to maximise their anti-tumour immune functions and prevent cancer spread. It is a completely novel approach that will allow for the more rational design of melanoma treatments that targets NK cells following surgery and local radiotherapy and/or chemotherapy.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
海外基金
