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JAK/STAT PATHWAY CONTROL OF CELL COMPETITION DURING DEVELOPMENT.

发育过程中细胞竞争的 JAK/STAT 通路控制。

基本信息

批准号：
8665757
负责人：
Erika A Bach
金额：
$ 8.48万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-12-01 至 2015-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8665757
关键词：
Address Apoptosis Apoptotic Area Binding Sites Biogenesis Biological Assay Bypass Caliber Candidate Disease Gene Cause of Death Cell Death Cells Cessation of life Characteristics Code Data Defect Development Diagnostic Neoplasm Staging Drosophila genus Emergency Situation Employee Strikes Floods Fluorescence-Activated Cell Sorting Fluorescent in Situ Hybridization Future Gene Targeting Genes Genetic Goals Growth Human Hurricane Immunofluorescence Immunologic Janus kinase Link Malignant Neoplasms Mammals Mechanics Mediating Medical center Metabolic Modeling Molecular Profiling Mus New York New York City Nucleic Acid Regulatory Sequences Orthologous Gene Pathway interactions Patient Care Phosphatidylinositols Phosphotransferases Plumbing Population Property Proteins Regenerative Medicine Regulation Reporting Research Ribosomes Rivers Role STAT protein Safety Signal Transduction Stem cells System Therapeutic Time Tissues Transcript Universities Validation Wing c-myc Genes design experience follow-up foot genome-wide killings transcription factor transcriptome sequencing tumorigenesis

项目摘要

Superstorm Sandy's effects on New York University Langone Medical Center (NYULMC): On October 29th, 2012, NYULMC experienced an unprecedented storm. A massive Hurricane with extremely high winds and a 14.2 foot storm surge struck New York City at high tide and flooded many areas of New York City, including NYULMC, which lies immediately adjacent to the East River (Figs. 1 & 2). The flooding at NYULMC caused damage that deeply impacted patient care, research, and educational facilities. NYULMC’s emergency power system was designed and built according to all safety codes to withstand a surge higher than the highest flood level for New York City in the past century. Superstorm Sandy obviously exceeded those levels. The main campus of NYULMC incurred extensive damage to its mechanical, electrical, and plumbing systems, requiring its temporary closure.

超级风暴桑迪对纽约大学朗格尼医学中心（NYULMC）的影响：10月29日， 2012年，NYULMC经历了一场前所未有的风暴。一场具有极高风速和 14.2一股高达30英尺的风暴潮在涨潮时袭击了纽约市，并淹没了纽约市的许多地区，包括 NYULMC，紧邻东河（图。1和2）。NYULMC的洪水造成了严重影响患者护理、研究和教育设施的损害。NYULMC的应急电源该系统的设计和建造符合所有安全规范，可承受比最高洪水更高的浪涌这是纽约市在过去世纪的最高水平。超级风暴桑迪显然超过了这些水平。主要 NYULMC校园的机械、电气和管道系统遭到了广泛的破坏，需要暂时关闭。