TAS::75 0872::TAS UTHSCSA CARDIOVASCULAR PROTEOMICS CENTER
TAS::75 0872::TAS UTHSCSA CARDIOVASCULAR PROTEOMICS CENTER
批准号:
8895199
负责人:
LANGE RICHARD ALLEN
金额:
$228.41万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-08-15 至 2015-08-14
关键词:
BiologicalBiological AssayBiological MarkersCardiacCardiovascular systemCatalogingCatalogsCellular biologyComputer SimulationEndothelial CellsExtracellular MatrixFibroblastsGenerationsHealth SciencesIn VitroLeft ventricular structureMyocardial InfarctionPathway interactionsPhysiologyProteomicsSignal PathwayTexasUniversitiesVentricular Remodelingclinical applicationdesignextracellularin vivoinnovationmacrophagemouse model
中文摘要
德克萨斯大学健康科学中心蛋白质组学中心提出将最先进的细胞外基质蛋白质组学和创新的计算建模方法与传统的生理学和细胞生物学分析相结合,以(a)识别心肌梗死后产生的关键细胞外片段,(b)确定调节左心室重构的细胞外片段信号通路。
英文摘要
The University of Texas Health Science Center Proteomics Center proposes a combination of state –of-the-art extracellular matrix proteomics and innovative computational modeling approaches with traditional physiology and cell biology assays to (a) identify key extracellular fragments generated post myocardial infarction and (b) determine the extracellular fragment signaling pathways that regulate left ventricle remodeling.
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TAS::75 0872::TAS UTHSCSA CARDIOVASCULAR PROTEOMICS CENTER
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批准号:8722947
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项目类别:
-
资助金额:$208.2万
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财政年份:2010
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负责人:LANGE RICHARD ALLEN
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依托单位:
海外基金