Food and Drug Administration Research FERN Chemistry Cooperative Agreement: MN De

明尼苏达州农业部 FDA食品安全和安保监测项目（U18），FERN化学实验室 RFA-FD-10-003摘要 摘要 明尼苏达州农业部（MDA）实验室服务部正在提交一份申请， FDA食品安全和安保监测项目（U18），FERN化学实验室，如RFD-FD-10-003中所述。 机构名称和地址：最高负责人： 明尼苏达州农业部加里霍瓦特，实验室主任 实验室服务部电话：651-201-6563 罗伯特街北601号 圣Paul，MN 55155 PD/PI： 主要电话：651-201-6010 Michelle坎贝尔，化学部门经理 总传真：651-201-6106电话：651-201-6575 MDA实验室自2004年以来一直是FERN微生物学和化学实验室。MDA实验室处于有利地位， 在其工作人员的经验和专业知识方面实现FDA FERN化学合作协议计划的目标， 设施，设备，并通过其持续参与FERN培训，监督，能力测试和合作 协议方案活动。 一个研究计划与项目叙述和支持文件提交的应用程序包解决： 计划公告中概述的四个关键项目领域 使用气相色谱-质谱（GC-MS）分析筛选和鉴定毒物，有毒 食品中的未知物质和未知化合物; 液相色谱-质谱（LC-MS）分析在毒物筛选和鉴定中的应用 食品中的未知物质和未知化合物; 电感耦合等离子体质谱法在重金属和有毒物质筛选鉴定中的应用 食物中的元素;以及， 使用酶联免疫吸附试验（ELISA）和其他基于抗体的分析方法进行筛选和鉴定 食物中的未知毒素 公告中的研究和相关其他项目信息部分涉及的具体问题包括： 实验室设施和其他资源 实验室人员资格 实验室管理规范 分析食品中未知污染物的实验室专业知识 设备 预算预测 样品分析承诺 研究计划和相关文件响应上述每个项目，并演示了MDA化学 实验室将为实现FDA食品安全和安全监测项目（U18）的目标做出贡献。 化学实验室。与FDA FERN达成合作协议的预期好处是， MDA工作人员的专业知识，以及通过MDA向FERN提供的重要实验室设施和设备资源。MDA 实验室工作人员将能够执行FERN监视任务、浪涌能力响应、能力测试，以及执行 针对各种食品基质中化学污染物的方法开发、验证和改进活动。 1

Minnesota Department of Agriculture FDA Food Safety and Security Monitoring Project (U18), FERN Chemical Laboratories Abstract for RFA-FD-10-003 ABSTRACT The Minnesota Department of Agriculture (MDA) Laboratory Services Division is submitting an application for consideration under the FDA Food Safety and Security Monitoring Project (U18), FERN Chemical Laboratories, as announced in RFD-FD-10-003. Facility name and address: Most responsible individual: Minnesota Department of Agriculture Gary Horvath, Laboratory Director Laboratory Services Division Phone: 651-201-6563 601 Robert Street North St. Paul, MN 55155 PD/PI: Main Phone: 651-201-6010 Michelle Campbell, Chemistry Section Manager Main Fax: 651-201-6106 Phone: 651-201-6575 The MDA Laboratory has been a FERN microbiology and chemistry laboratory since 2004. The MDA Laboratory is well-positioned to carry out the goals of the FDA FERN chemistry cooperative agreement program in terms of the experience and expertise of its staff, facilities, equipment, and through its on-going participation in FERN training, surveillance, proficiency testing, and cooperative agreement programs activities. A Research Plan with project narrative and supporting documentation is submitted in the application package addressing: Four key project areas outlined in the program announcement Use of Gas Chromatograph - Mass Spectrometry (GC-MS) analysis for the screening and identification of poisons, toxic substances, and unknown compounds in foods; Use of Liquid Chromatograph - Mass Spectrometry (LC-MS) analysis for the screening and identification of poisons, toxic substances, and unknown compounds in foods; Use of Inductively Coupled Plasma - Mass Spectrometry for the screening and identification of heavy metals ands toxic elements in food; and, Use of Enzyme-Linked Immunosorbent Assay (ELISA) and other antibody-based analysis for the screening and identification of unknown toxins in foods. Specific issues addressed in the Research and Related Other Project Information portion of the announcement include: Laboratory Facilities and Other Resources Laboratory Personnel Qualifications Laboratory Management Practices Laboratory Expertise in Analyzing Foods for Unknown Contaminants Equipment Budget Projection Sample Analysis Commitment The research plan and associated documentation responds to each item outlined above, and demonstrates how the MDA Chemistry Laboratory will contribute toward meeting the objectives of the FDA Food Safety and Security Monitoring Project (U18) for FERN Chemical Laboratories. The expected benefit of this cooperative agreement to FDA FERN is to leverage the considerable experience and expertise of the MDA staff, and the significant laboratory facilities and equipment resources available to FERN through MDA. MDA laboratory staff will be able to carry out FERN surveillance assignments, surge capacity response, proficiency tests, as well as, perform method development, validation and enhancement activities for chemical contaminants in a variety of food matrices. 1