Food and Drug Administration Research FERN Chemistry Cooperative Agreement: MN De

美国食品药品监督管理局研究 FERN 化学合作协议：MN De

• 批准号: 8698420
• 负责人: Michelle Dawn Campbell
• 金额: $ 37.86万
• 依托单位: MINNESOTA STATE DEPT OF AGRICULTURE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8698420
• 关键词: Food; Drug; Administration; Research; FERN

Minnesota Department of Agriculture FDA Food Safety and Security Monitoring Project (U18), FERN Chemical Laboratories Abstract for RFA-FD-10-003 ABSTRACT The Minnesota Department of Agriculture (MDA) Laboratory Services Division is submitting an application for consideration under the FDA Food Safety and Security Monitoring Project (U18), FERN Chemical Laboratories, as announced in RFD-FD-10-003. Facility name and address: Most responsible individual: Minnesota Department of Agriculture Gary Horvath, Laboratory Director Laboratory Services Division Phone: [phone] Robert Street North St. Paul, MN 55155 PD/PI: Main Phone: [phone] Michelle Campbell, Chemistry Section Manager Main Fax: [phone] Phone: [phone] The MDA Laboratory has been a FERN microbiology and chemistry laboratory since 2004. The MDA Laboratory is well-positioned to carry out the goals of the FDA FERN chemistry cooperative agreement program in terms of the experience and expertise of its staff, facilities, equipment, and through its on-going participation in FERN training, surveillance, proficiency testing, and cooperative agreement programs activities. A Research Plan with project narrative and supporting documentation is submitted in the application package addressing: Four key project areas outlined in the program announcement Use of Gas Chromatograph - Mass Spectrometry (GC-MS) analysis for the screening and identification of poisons, toxic substances, and unknown compounds in foods; Use of Liquid Chromatograph - Mass Spectrometry (LC-MS) analysis for the screening and identification of poisons, toxic substances, and unknown compounds in foods; Use of Inductively Coupled Plasma - Mass Spectrometry for the screening and identification of heavy metals ands toxic elements in food; and, Use of Enzyme-Linked Immunosorbent Assay (ELISA) and other antibody-based analysis for the screening and identification of unknown toxins in foods. Specific issues addressed in the Research and Related Other Project Information portion of the announcement include: Laboratory Facilities and Other Resources Laboratory Personnel Qualifications Laboratory Management Practices Laboratory Expertise in Analyzing Foods for Unknown Contaminants Equipment Budget Projection Sample Analysis Commitment The research plan and associated documentation responds to each item outlined above, and demonstrates how the MDA Chemistry Laboratory will contribute toward meeting the objectives of the FDA Food Safety and Security Monitoring Project (U18) for FERN Chemical Laboratories. The expected benefit of this cooperative agreement to FDA FERN is to leverage the considerable experience and expertise of the MDA staff, and the significant laboratory facilities and equipment resources available to FERN through MDA. MDA laboratory staff will be able to carry out FERN surveillance assignments, surge capacity response, proficiency tests, as well as, perform method development, validation and enhancement activities for chemical contaminants in a variety of food matrices. 1

明尼苏达州农业部 FDA 食品安全和安保监测项目 (U18)，FERN 化学实验室 RFA-FD-10-003 摘要 抽象的 明尼苏达州农业部 (MDA) 实验室服务部正在提交一份申请，以供考虑 FDA 食品安全和安保监测项目 (U18)，FERN 化学实验室，如 RFD-FD-10-003 中所宣布。 设施名称和地址： 最负责人： 明尼苏达州农业部 Gary Horvath，实验室主任 实验室服务部电话：651-201-6563 罗伯特北街601号 圣保罗，明尼苏达州 55155 PD/PI： 主要电话：651-201-6010 Michelle Campbell，化学科经理 主要传真：651-201-6106 电话：651-201-6575 自 2004 年以来，MDA 实验室一直是 FERN 微生物学和化学实验室。MDA 实验室处于有利位置： 根据其员工的经验和专业知识实现 FDA FERN 化学合作协议计划的目标， 设施、设备，并通过持续参与 FERN 培训、监督、能力验证和合作 协议计划活动。 包含项目说明和支持文件的研究计划在申请包中提交，地址为： 计划公告中列出的四个重点项目领域 使用气相色谱-质谱（GC-MS）分析来筛选和鉴定毒物、有毒物质 食品中的物质和未知化合物； 使用液相色谱-质谱（LC-MS）分析来筛选和鉴定毒物、有毒物质 食品中的物质和未知化合物； 使用电感耦合等离子体-质谱法筛选和鉴定重金属和有毒物质 食物中的元素；和， 使用酶联免疫吸附测定 (ELISA) 和其他基于抗体的分析进行筛选和鉴定 食物中未知的毒素。 公告的研究和相关其他项目信息部分解决的具体问题包括： 实验室设施和其他资源 实验室人员资质 实验室管理实践 分析食品中未知污染物的实验室专业知识 设备 预算预测 样品分析承诺 研究计划和相关文件对上述每一项进行了回应，并展示了 MDA 化学如何 实验室将致力于实现 FERN 的 FDA 食品安全和安保监测项目 (U18) 的目标 化学实验室。此次合作协议对 FDA FERN 的预期好处是利用丰富的经验 和 MDA 工作人员的专业知识，以及通过 MDA 向 FERN 提供的重要实验室设施和设备资源。丙二醛 实验室工作人员将能够执行 FERN 监视任务、激增能力响应、能力测试以及执行 针对各种食品基质中化学污染物的方法开发、验证和增强活动。 1