2014 Cellular and Molecular Fungal Biology Gordon Research Conference

描述(由申请人提供)：本申请请求部分资助将于2014年6月15-20日在霍尔德内斯学院举行的细胞和分子真菌生物学戈登研究会议。会议的广泛和长期目标是增加我们对基本真菌生物学及其在社会重要问题上的应用的集体理解。真菌会导致重要的人类疾病，许多提出的研究将直接涉及NIH-国家过敏和传染病研究所的兴趣。此外，真菌是最好和最容易处理的真核模式生物之一；从广义上讲，几乎所有的会议都将是NIH-国家普通医学科学研究所目标的中心。这次会议的具体目的将是召集真菌生物学，包括细胞/分子、系统和进化生物学方面前所未有的各种专业知识的与会者，以探讨真菌如何在其环境中生长、繁殖、与其他生物相互作用和发挥作用。大约140名与会者中的46位演讲者将在一个几乎没有分心的环境中相聚五天。大约90张海报将分三班展示。口头会议和海报会议旨在简洁和有效地传播未公布的成果，重点是讨论和建立联系；过去各次会议的评价证明了这种形式的有效性。2014年的会议将以代表全方位真菌生物学的新研究为特色，包括基因组动力学、微生物群、系统生物学、进化和种群基因组学、发病机制和共生以及细胞生物学。这一应用的意义在于，这次会议在加速国际真菌生物界的研究，包括疾病的预防和治疗方面取得了显著的效果。这一应用的健康相关性集中在真菌在人类疾病中的作用，包括三种最重要的移植和其他免疫功能受损患者的疾病，念珠菌病、隐球菌病和曲霉病，以及感染免疫能力强的患者的系统性真菌疾病，如球虫。

DESCRIPTION (provided by applicant): This application requests partial support for the Gordon Research Conference on Cellular and Molecular Fungal Biology to be held at the Holderness School, June 15-20, 2014. The broad and long-term goal of the conference is to increase our collective understanding of basic fungal biology and its application to socially important problems. Fungi cause important human diseases, and much of the research presented will directly address the interests of the NIH-National Institute of Allergy and Infectious Disease. Furthermore, fungi are among the best and most tractable eukaryotic model organisms; in the broad sense, almost all of the conference will be central to the aims of NIH-National Institute of General Medical Science. The specific aim of this meeting will be to convene participants of an unprecedented range of expertise in fungal biology, including cell/molecular, systems, and evolutionary biology in order to address how fungi grow, reproduce, interact with other organisms, and function in their environments. The 46 speakers among approximately 140 attendees will be together for five days in a setting with few distractions. Approximately 90 posters will be presented in three shifts. The oral and poster sessions are designed for succinct and efficient communication of unpublished results with emphasis on discussion and networking; evaluations from past conferences demonstrate the effectiveness of this format. The 2014 meeting will feature new research representing the full range of fungal biology including genome dynamics, microbiomes, systems biology, evolutionary and population genomics, pathogenesis and symbiosis, and cell biology. The significance of this application is the demonstrated effect of this conference in accelerating research in the international fungal biology community, including prevention and treatment of disease. The health relatedness of this application centers on the role of fungi in human disease, including three of the most important diseases of transplant and other immunocompromised patients, candidiasis, cryptococcosis and aspergillosis, as well as systemic fungal diseases that infect immunocompetent patients such as coccidiodes.