Core A: Administrative Core

核心A：行政--摘要 加州大学圣迭戈分校阿尔茨海默病研究中心(ADRC)在以下方面为研究进展做出了巨大贡献 在过去的30年里。在更新期间，中心将保持强有力的行政管理，以 设定目标和方向，为调查人员维护支持性环境，管理核心、项目和 人员，并与大学管理部门、NIH和其他中心的研究人员互动。亚洲发展研究中心 将强调3个研究主题：1)AD早期阶段的详细表型，包括轻度认知 损害(MCI)与临床前AD；2)非AD痴呆研究；3)基础研究 阿尔茨海默病和相关疾病的神经退行性变，强调翻译研究。 行政核心的具体目标包括： 1)向ADRC提供全面的科学领导并推进其使命，确保资源 可用。2)监督和支持亚洲发展研究中心的核心和项目。3)构建协同效应和协作 与加州大学圣地亚哥分校和退伍军人医学中心的临床医生和研究人员合作。4)继续和加强协作 与圣地亚哥其他杰出生物医学研究机构的研究人员合作。5)合作伙伴 社区组织和卫生保健网络，以促进教育和加强招聘。这 包括阿尔茨海默氏症协会和其他患者组织，以及圣地亚哥的普通医生 医疗保健组织。6)每年征集先导研究项目，安排评审并提交NIA。7)提供 对该中心进行健全的财务管理。8)每年与我们的外部咨询沟通并召开会议 冲浪板。9)与其他ADC、NACC和ADC互动，以支持多个ADC项目和倡议， 包括临床试验。10)与NIA和NACC保持联系，并参加半年度的全国性AD中心会议。 11)确保ADRC工作人员了解并遵守法规。12)维护详细的 并更新网站，突出ADRC的研究，面向公众和研究人员。

CORE A: ADMINISTRATIVE - ABSTRACT The UCSD Alzheimer's Disease Research Center (ADRC) has contributed greatly to research progress in the past 30 years. Strong administrative management of the Center will be maintained during the renewal to set goals and direction, maintain a supportive environment for investigators, manage Cores, projects and personnel, and interact with University Administration, NIH, and researchers at other Centers. The ADRC will emphasize 3 research themes: 1) detailed phenotyping of early stages of AD, including Mild Cognitive Impairment (MCI) and preclinical AD; 2) research into non-AD dementias; 3) Basic studies of neurodegeneration in AD and related disorders, emphasizing translational research. Specific Aims of the Administrative Core include: 1) Provide overall scientific leadership to the ADRC and advance its mission, ensuring that resources are available. 2) Oversee and support Cores and Projects of the ADRC. 3) Build synergy and collaborations with clinicians and researchers at UCSD and VA Medical Center. 4) Continue and strengthen collaboration with researchers at other outstanding biomedical research institutions in San Diego. 5) Partner with community organizations and health care networks to advance education and enhance recruitment. This includes the Alzheimer Association and other patient organizations, and physicians at large San Diego HMOs. 6) Solicit Pilot research projects each year, arrange for review and submission to NIA. 7) Provide sound fiscal management for the Center. 8) Communicate and meet annually with our External Advisory Board. 9) Interact with other ADCs, NACC and ADCS to support multi-ADC projects and initiatives, including clinical trials. 10) Liaise with NIA and NACC and attend semi-annual national AD Center meetings. 11) Ensure that ADRC staff are knowledgeable about and comply with regulations. 12) Maintain a detailed and updated website to highlight ADRC research, for the public and researchers.