2014 Ion Channels Gordon Research Conference

描述（由申请人提供）：本提案是作为对离子通道国际会议的部分支持请求提交的，该会议是戈登研究会议系列的一部分，将于2014年7月6日至11日在马萨诸塞州南哈德利的霍利奥克山学院举行。本次会议的长期目标是增加对离子通道的基本结构，功能和生理作用以及它们在人类疾病中的功能障碍和调节的理解。本次会议的具体目标是召集代表离子通道研究关键领域的40名发言人和讨论负责人以及140名普通与会者，最多180名与会者，在相对隐蔽的环境中举行为期五天的会议。对于2014年的会议，我们将特别致力于加强基本机制理解与生理和疾病机制的联系。为了鼓励这一结果，会议已经围绕离子通道的“生命”主题发展，而不是传统上采用的相对无关的主题会议。该计划将包括九个会议，解决目前的问题，在离子通道机制在人类健康和疾病。此外，四次海报会议将使所有广大与会者能够介绍他们自己关于这些专题的工作。本次会议的重要性在于，作为在国际离子通道生物学家界丰富思想和研究的既定会议中讨论基本机制的首要会议。离子通道研讨会规模小，讨论激烈，这使得它对参与者中新思想和新方向的催化作用具有独特的重要性。这一应用与健康有关，讨论将确定在影响人类发展和健康的各种领域需要实验解决的问题。

DESCRIPTION (provided by applicant): This proposal is submitted as a request for partial support for an international meeting on Ion Channels, as part of the Gordon Research Conference series, to be held at Mount Holyoke College in South Hadley, Massachusetts, July 6 - 11, 2014. The long-term goal of this conference is to increase understanding of the fundamental structure, function and physiological roles of ion channels as well as their dysfunction and modulation in human disease. The specific aim of this meeting will be to convene 40 speakers and discussion leaders that represent critical areas of ion channel research together with 140 participants-at-large for a maximum of 180 participants for a five-day meeting in a relatively secluded setting. For the 2014 meeting we will specifically aim to strengthen the linking of fundamental mechanistic understanding to physiological and disease mechanisms. To encourage this outcome, the sessions have been thematically developed around the 'life' of ion channels, rather than the relatively unconnected topic sessions that have traditionally been employed. The program will consist of nine sessions that address current issues in ion channel mechanisms in human health and disease. In addition, four poster sessions will permit all participants-at-large to present their own work on these topics. The significance of this meeting is as the premier meeting for discussion of fundamental mechanisms among the established meetings that fertilize ideas and research in the international community of ion channel biologists. The small size and intensive discussions engendered by the Ion Channels GRC make it uniquely important for the catalysis of new ideas and directions among the participants. The health-relatedness of this application is that the discussions will define questions that require experimental resolution in a wide variety of areas that affect human development and health.