2/2-Treatment of Feeding Problems in Children with Autism

2/2-自闭症儿童喂养问题的治疗

• 批准号: 8636720
• 负责人: SUSAN L HYMAN
• 金额: $ 22.97万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-02-03 至 2017-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8636720
• 关键词: Achievement; Address; Adherence; Aftercare; Age; Autistic Disorder; Behavior; Behavior Therapy; Behavioral; Bite; Caregivers; Child; Child Nutrition; Child health care; Childhood; Control Groups; Data; Data Collection; Day Care; Development; Diagnosis; Diet; Diet Monitoring; Diet and Nutrition; Eating; Enrollment; Epidemiology; Equipment and supply inventories; Evaluation; Exhibits; Family; Food; Food Aversion; Future; Goals; Health Services Research; Home environment; Inpatients; Intervention; Intervention Studies; Literature; Measurement; Measures; Mental disorders; Modeling; Monitor; NIH Program Announcements; Nutritional; Nutritional status; Outcome; Outpatients; Parent-Child Relations; Parenting behavior; Parents; Participant; Pilot Projects; Population; Prevalence; Problem behavior; Procedures; Protocols documentation; Psychopharmacology; Questionnaires; Randomized; Randomized Clinical Trials; Records; Recruitment Activity; Reporting; Research; Research Personnel; Ritual compulsion; Sampling; Schedule; Schools; Sensory; Services; Shapes; Site; Stress; Testing; Time; Training; Training Programs; Treatment Efficacy; Universities; Waiting Lists; autism spectrum disorder; base; cost effective; data management; design; efficacy testing; experience; feeding; flexibility; indexing; innovation; non-compliance; nutrition; parental involvement; primary outcome; programs; psychosocial; public health relevance; response; success; tool; treatment center; treatment duration

DESCRIPTION (provided by applicant): An estimated 46-89% of children with Autism Spectrum Disorders (ASD) have feeding problems such as idiosyncratic food selectivity and food refusal, food aversion, mealtime rituals and disruptive behaviors at mealtime. For children with ASD whose development is already compromised by a range of deficits, the potential impact of feeding, eating and any resulting nutritional problems may be far reaching. The limited treatment literature suggests behavioral interventions can be effective in addressing the array of feeding problems in this population. However, randomized clinical trials of these interventions are currently unavailable. In addition, the interventions have primarily been delivered in highly specialized settings (inpatient or day treatment centers that have feeding experts on staff) with little parental involvement. To our knowledge, a systematic parent training model to specifically address feeding problems in young children with ASD in outpatient settings, which may be more widely accessible and efficient than inpatient or day treatment, has not been investigated. In response to Program Announcement PAR-12-071 (Collaborative R34s for Pilot Studies of Innovative Treatments in Mental Disorders) and PA-11-283 (Psychosocial/Behavioral Interventions and Services Research in Autism Spectrum Disorders), this two-site project will develop and then pilot a 11-session behavioral parent training program for feeding problems (PT-F) using a wait-list control design. Participants are 50 children with ASD, age 2-7 years, and their caregivers. Primary outcomes are changes in the child's mealtime behavior. Other outcomes center on changes in parent-child interactions. Both sites (Pittsburgh and Rochester) have extensive experience in multisite trials, development of parent training protocols, and evaluation of diet and nutrition. The Epidemiology Data Center (EDC) at the University of Pittsburgh's Graduate School of Public will provide data management and biostatistical services. Rochester will oversee protocols for monitoring children's diets and nutritional status brings together investigators with experience in parent training and in feeding and nutrition. Both sites will contribute to the development of PT-F.

描述(由申请人提供)：据估计，46%-89%的自闭症谱系障碍(ASD)儿童有进食问题，如特殊的食物选择性和食物拒绝、食物厌恶、用餐仪式和用餐时的扰乱行为。对于患有自闭症的儿童来说，他们的发育已经受到一系列缺陷的影响，喂养、饮食和任何由此产生的营养问题的潜在影响可能是深远的。有限的治疗文献表明，行为干预可以有效地解决这一人群中的一系列喂养问题。然而，这些干预措施的随机临床试验目前还不可用。此外，干预措施主要在高度专业化的环境中提供(住院或日间治疗中心，工作人员有喂养专家)，几乎没有父母的参与。据我们所知，专门解决自闭症儿童在门诊环境中喂养问题的系统父母培训模式尚未得到调查，这种模式可能比住院或日间治疗更广泛和更有效。作为对项目公告PAR-12-071(精神疾病创新治疗试点研究的协作R34)和PA-11-283(自闭症谱系障碍的心理社会/行为干预和服务研究)的回应，这个两个站点的项目将开发并试点一个为期11节的喂养问题(PT-F)父母行为培训计划，采用等待名单控制设计。参与者是50名患有自闭症的儿童，年龄2-7岁，以及他们的照顾者。主要结果是孩子就餐时行为的变化。其他结果集中在亲子互动的变化上。这两个站点(匹兹堡和罗切斯特)在多站点试验、父母培训方案的制定以及饮食和营养评估方面都有丰富的经验。匹兹堡大学公共研究生院的流行病学数据中心将提供数据管理和生物统计服务。罗切斯特将监督监测儿童饮食和营养状况的协议，并将具有父母培训以及喂养和营养经验的调查人员聚集在一起。两者都有 场址将为PT-F的发展做出贡献。