Potassium Level Monitoring System

钾浓度监测系统

• 批准号: 8713146
• 负责人: PAUL L GIBSON
• 金额: $ 22.43万
• 依托单位: ADVANCED MEDICAL ELECTRONICS CORPORATION
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8713146
• 关键词: Address; Affect; Algorithms; Ambulatory Care; Applications Grants; Area; Arrhythmia; Blood; Blood Tests; Boston; Calcium; Cardiac; Cardiovascular Diseases; Cardiovascular system; Cessation of life; Chemicals; Chronic; Clinic; Clinical; Clinical Medicine; Clinical Trials; Collaborations; Communication; Computer software; Consult; Devices; Diagnostic; Dialysis procedure; Disease; Diuretics; Doctor of Philosophy; Echocardiography; Economics; Elderly; Electrocardiogram; Electrolytes; Electronics; Engineering; Evaluation; FDA approved; Fostering; Functional disorder; Glucose; Health; Heart Diseases; Heart failure; Home environment; Homeostasis; Hospitalization; Hospitals; Hypokalemia; Implant; Inborn Genetic Diseases; Independent Living; Kidney Diseases; Kidney Failure; Lead; Left; Magnesium; Measurement; Measures; Medical; Medical Electronics; Methods; Modality; Monitor; Morbidity - disease rate; Operative Surgical Procedures; Outpatients; Patient Care; Patient Monitoring; Patients; Pharmaceutical Preparations; Phase; Physicians; Physiological; Population; Potassium; Principal Component Analysis; Principal Investigator; Process; Provider; Puncture procedure; Records; Renal Glycosuria; Research; Research Personnel; Risk; Running; Secondary to; Signal Transduction; Skin; Sodium; Specific qualifier value; System; Technology; Telemetry; Time; To specify; Venous blood sampling; Virend; Visit; care delivery; design; heart rhythm; human study; improved; innovative technologies; instrument; minimally invasive; mortality; novel; prevent; programs; prototype; public health relevance; response; sensor; signal processing; subcutaneous; thiazide; tool

DESCRIPTION (provided by applicant): Advanced Medical Electronics (AME) and our partners propose a minimally-invasive system for continuous monitoring of potassium. Measurement of blood levels of potassium is important in clinical medicine. Abnormalities of potassium, common in heart and kidney disease, can be aggravated by many medications used to treat these disorders leading to arrhythmias and death. Determination of potassium values has always required access to blood - either by phlebotomy or other skin puncture. The proposed project involves developing a minimally invasive technology that permits determining potassium values without obtaining blood, by recording the body's own response to potassium levels, thereby increasing comfort and convenience for the patient. This technology can be applied in the hospital or at home, extending a remote monitoring platform, and promoting independence and wellness by permitting medication adjustments without hospitalization for frequent blood tests. The ability to manage patients remotely and thereby identify and address health issues early and without need for a clinical visit and blood draw improves care for patients and increases the economic efficiency of care delivery for payors and providers. A prototype system will be developed and evaluated in phase 1.

描述（由申请人提供）：Advanced Medical Electronics（AME）和我们的合作伙伴提出了一种用于连续监测钾的微创系统。血液中钾离子浓度的测定在临床医学中具有重要意义。钾的缺乏，常见于心脏病和肾病，可加重许多药物用于治疗这些疾病，导致心律失常和死亡。钾值的测定总是需要血液-通过静脉切开术或其他皮肤穿刺。拟议的项目涉及开发一种微创技术，通过记录人体对钾水平的反应，在不采集血液的情况下测定钾值，从而增加患者的舒适度和便利性。这项技术可以应用在医院或家中，扩展远程监控平台，并通过允许药物调整而无需住院进行频繁的血液检查来促进独立性和健康。远程管理患者的能力，从而及早识别和解决健康问题，而无需临床访问和抽血，改善了对患者的护理，并提高了支付者和提供者提供护理的经济效率。第一阶段将开发和评价一个原型系统。