RCU for Lifestyle Interventions in Overweight and Obese Pregnant Women Consortium

描述(由申请人提供)：超重和肥胖孕妇联合会生活方式干预的总体目标是确定有效的行为和生活方式干预措施，以改善肥胖和超重孕妇的体重、血糖控制和其他与怀孕相关的结果，并确定这些干预措施是否可以减少其子女的肥胖和代谢异常。该联盟将由临床中心和一个研究协调单位组成。该联盟内的每个临床中心将设计和进行一项干预性研究。-研究协调股将通过促进研究调查人员和国家卫生研究院之间的合作、协调和科学信息交流，提高这一研究方案的价值。这些目标将通过以下方式实现：为会议和电话会议提供后勤和行政支助，设计和维护内部信息交流网站，编写报告，链接数据集，传播成果，编制供公众使用的有限访问数据集。研究协调股将协助设计和实施干预性研究，并将通过实施共同的措施和方法，促进设计跨研究的综合分析。此外，RCU将根据联盟目标的要求协助数据管理、质量控制和统计分析。

DESCRIPTION (provided by applicant): The overall goal of the Lifestyle Interventions in Overweight and Obese Pregnant Women Consortium is to identify effective behavioral and lifestyle interventions that will improve weight, glycemic control and other-pregnancy-related outcomes in obese and overweight pregnant women, and determine whether these interventions reduce obesity and metabolic abnormalities in their children. The Consortium will consist of clinical centers and a Research Coordinating Unit. Each clinical center within the Consortium will design and conduct an interventional study. -The Research Coordinating Unit will enhance the value of this research program by promoting collaboration, coordination and exchange of scientific information among the research investigators and NIH. These goals will be achieved by providing logistical and administrative support for meetings and calls, designing and maintaining an internal website for information exchange, preparing reports, linking datasets, disseminating results, and preparing limited access datasets for public use. The Research Coordinating Unit will assist with the design and implementation of the interventional studies, and will facilitate the design of the combined analyses across the studies by implementing common measures and methods. Additionally, the RCU will assist with data management, quality control and statistical analysis as required by the goals of the Consortium.