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中文摘要
翻译
核心A协调完成孔特中心科学任务所需的资源和设施。它有四个相辅相成的职能:1.对调查人员、受训人员和人员进行行政协调,包括执行NIH、大学和IRB的指导方针,分配资源,提交进度报告,审查新的倡议,与大学和社区联系,制定政策。2.研究人员、受训者和人员之间的学术协调包括沟通、整合教育活动、与神经科学项目联系、招募合格受训者。康特中心将向社区维持一个全面的外展计划,通过在地方、地区和国家会议上的演讲者以及以开放的形式邀请公众到宾夕法尼亚大学,帮助传播有关精神分裂症的基础和临床神经科学研究的信息。通过核心B和项目,该核心协调中心的网站,确保获取中心产生的数据、研究工具和生物材料,并促进与咨询委员会的互动。3.人力资源项目的征聘和评估(一、四、五)。标准化的程序适用于患有精神分裂症的青少年、易患精神病的人和健康的人。这包括对医疗、神经和精神状态的评估、计算机化的神经认知测量和基因分型。该中心为项目IV和V中的脑部捐献用于尸检研究的个人提供系统的临床历史和陈述评估,并协调数据传输到数据和生物统计核心(核心B)和项目(L、IV、V)。Core A为未来的研究和综合项目维护注册,并在该中心和合作项目中提供临床神经科学方面的培训。4.动物项目参与者的分配提供了方案的协调,与核心B一起跟踪参与者在项目二、项目三和项目四之间的流动,并与动物项目的调查人员和研究人员密切合作,以确保实现科学目标。这是与人体研究并行进行的,保持了整个中心的高度整合。
英文摘要
Core A coordinates the resources and facilities necessary for attaining the scientific mission of the Conte Center. It has four complementary functions: 1. Administrative Coordination to investigators, trainees and personnel includes implementation of NIH, University and IRB guidelines, allocation of resources, progress reports, review new initiatives, provide liaison with University and Community, establish policies. 2. Academic Coordination among investigators, trainees and personnel includes communication, integration of educational activities, liaison with neuroscience programs, recruitment of qualified trainees. The Conte Center will maintain a comprehensive outreach program to the community that contributes to dissemination of information regarding basic and clinical neuroscience research in schizophrenia through speakers in local, regional and national meetings and in an open-house format, inviting the public to Penn. With Core B and Projects, this Core coordinates the Center's website, ensure access to data, research tools and biological material generated by the Center, and facilitate interaction with the Advisory Board. 3. Recruitment and Assessment for human Projects (I, IV,V). Standardized procedures are applied to youths with schizophrenia, psychosis- prone and healthy people. This includes evaluation of medical, neurological and psychiatric status, computerized neurocognitive measures and genotyping. The Core provides systematic assessment of clinical history and presentation of individuals whose brains are donated for postmortem research in Projects IV and V and coordinates data transfer to Data and Biostatistics Core (Core B) and Projects (l,IV,V). Core A maintains a registry for future studies and integrative projects, and provide training in clinical neuroscience in the Center and collaborating programs. 4. Allocation of participants to animal projects provides coordination of the protocols, tracking with the Core B the flow of participants across Projects II, III and IV and works closely with investigators and research personnel in the animal projects to ensure that the scientific goals are met. This is done in parallel to the human studies maintaining high level of integration across the Center.
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Evolution of Psychosis in Youth: Multimodal Risk and Resilience Markers
  • 批准号:
    10401818
  • 项目类别:
  • 资助金额:
    $72.62万
  • 财政年份:
    2019
  • 负责人:
    Raquel E Gur
  • 依托单位:
1/9: Dissecting the effects of genomic variants on nenriched for neuropsychiatric disorderseurobehavioral dimensions in CNVs
  • 批准号:
    10088064
  • 项目类别:
  • 资助金额:
    $38.78万
  • 财政年份:
    2019
  • 负责人:
    Raquel E Gur
  • 依托单位:
Evolution of Psychosis in Youth: Multimodal Risk and Resilience Markers
  • 批准号:
    10612018
  • 项目类别:
  • 资助金额:
    $71.46万
  • 财政年份:
    2019
  • 负责人:
    Raquel E Gur
  • 依托单位:
1/9: Dissecting the effects of genomic variants on nenriched for neuropsychiatric disorderseurobehavioral dimensions in CNVs
  • 批准号:
    10597092
  • 项目类别:
  • 资助金额:
    $74.77万
  • 财政年份:
    2019
  • 负责人:
    Raquel E Gur
  • 依托单位:
海外基金