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Targeting the PI3K Pathway in Malignant Glioma

Targeting the PI3K Pathway in Malignant Glioma
靶向恶性胶质瘤中的 PI3K 通路
批准号：
8753977
负责人：
W K ALFRED Yung
金额：
$22.24万
依托单位：
UNIVERSITY OF TX MD ANDERSON CAN CTR
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
未结题
起止时间：
2008-09-01 至
来源：
https://reporter.nih.gov/project-details/8753977
关键词：
1-Phosphatidylinositol 3-KinaseAddressAftercareAnimalsBayesian MethodBehaviorBiologicalBiological MarkersCell LineCell ProliferationCell modelCellsClinicClinical TrialsCombined Modality TherapyCompanionsDataData SetFailureFrequenciesFundingGene MutationGene TargetingGenomicsGlioblastomaGliomaGrantGrowthHumanIn VitroIndividualMalignant GliomaMalignant neoplasm of brainMetabolismMethodsMolecularMolecular ProfilingOperative Surgical ProceduresPathway interactionsPatient SelectionPatientsPatternPhase I Clinical TrialsPopulationProteinsProteomicsRNA InterferenceRandomizedRecurrenceRegulatory PathwayRoleSamplingSignal PathwaySignal TransductionSpecimenStem cellsTestingThe Cancer Genome AtlasTimeTreatment FailureTreatment outcomeUp-RegulationValidationangiogenesisarmbasecancer stem cellcancer therapycombinatorialdesignexperiencehuman FRAP1 proteinimprovedin vivoinhibitor/antagonistkinase inhibitormalignant phenotyperesistance mechanismresponsesmall hairpin RNAsmall moleculestemtumor

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