UIC Center for Population Health and Health Disparities

UIC人口健康和健康差异中心

• 批准号: 8703617
• 负责人: RICHARD WARNECKE
• 金额: $ 162.53万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8703617
• 关键词: Address; Adherence; Affect; Benefits and Risks; Biological; Biological Factors; Breast Cancer Detection; Cancer Control; Centers for Population Health; Clinic; Color; Community Health; DNA Methylation; Diagnosis; Early Diagnosis; Ensure; Ethnic Origin; Evaluation; Funding; Genetic; Glass; Guidelines; Health Services Accessibility; Hospitals; Intervention; Lead; Malignant Neoplasms; Mammography; Medically Underserved Area; Modeling; Monitor; National Cancer Institute; Outcome; Paper; Patient Monitoring; Patients; Policies; Principal Investigator; Publications; Race; Research; Research Training; Risk; Staging; TNFRSF5 gene; Testing; Training; Underrepresented Minority; United States National Institutes of Health; Vision; Woman; Work; base; breast cancer diagnosis; cancer care; career development; data management; health disparity; improved; malignant breast neoplasm; multidisciplinary; population health; programs; safety net; screening

DESCRIPTION (provided by applicant): This proposal is for renewal of the UlC-Center for Population Health and Health Disparities (P50 CA10674). This Center is one of five that were funded in whole or in part by the National Cancer Institute as part of the initial NIH initiative. It is a Multiple Principal Investigator application. The center theme is: Understanding how our previous research identifying fundamental causes of disparities in stage at breast cancer diagnosis related to race/ethnicity can lead to interventions grounded in that research? The current aims of the proposed renewal of the Center are to address three questions that have emerged as central issues in understanding the disparity in stage at breast cancer diagnosis between White women and women of color based on our work to date. These are: I) To define how apparent disparities in early detection, diagnosis and treatment can be addressed in safety-net hospitals? 2a) Determine how community health clinics can more effectively identify and monitor patients at risk for aggressive breast cancer. 2b) Determine how patients at elevated risk can be engaged to participate in a tailored screening and monitoring program. 3) To determine how biological factors, specifically DNA methylation, promote aggressive breast cancer disproportionately among women of color? . There are three projects: .1) Patient Navigation in Medically Underserved Areas. (E. Calhoun, PI) 2) A Breast Cancer Screening Intervention to Improve Adherence to Cancer Control Guidelines in Underserved Minority Women (K. Hoskins, PI); DNA Methylation and Differential Cancer Aggressiveness by Race/Ethnicity (G. Rauscher, PI) and four cores: Administration (R. Warnecke (Contact) & E. Calhoun (Co- Core leaders); Policy and Dissemination (C. Ferrans, CL); Data Management and Evaluation (T. Johnson, (CL) and Training and Career Development (F Davis, CL ) Our continuing, long range vision is to test and establish interventions that address determinants of population health disparities by approaching them with a multilevel and multidisciplinary population health strategy. To accomplish this we will: 1) conduct research that impacts the policies that govern access to mammography and management of breast cancer and ensures equal access to the standard of breast cancer care regardless of where it is delivered and who requests it. 2) Enable women who are poor and underserved to recognize the need to access the care in ways that ensure the best outcomes. 3) To train young scholars in health disparities research incorporating a transdisciplinary research perspective.

描述(由申请人提供)：本建议书用于更新ULC--人口健康和健康差距中心(P50 CA10674)。作为美国国立卫生研究院最初倡议的一部分，该中心是由国家癌症研究所提供全部或部分资金的五个中心之一。这是一个多主体调查员应用程序。中心主题是：了解我们之前的研究如何确定与种族/民族相关的乳腺癌诊断阶段差异的根本原因，从而导致以该研究为基础的干预？根据我们迄今的工作，目前提议更新该中心的目的是解决三个问题，这三个问题已成为了解白人女性和有色人种女性乳腺癌诊断阶段差异的核心问题。它们是：i)确定如何在安全网医院中解决早期发现、诊断和治疗方面的明显差异？2)确定社区卫生诊所如何更有效地识别和监测有侵袭性乳腺癌风险的患者。2B)确定如何让高风险患者参与量身定制的筛查和监测计划。3)确定生物因素，特别是DNA甲基化，如何在有色人种女性中不成比例地促进侵袭性乳腺癌？有三个项目：1)在医疗服务不足的地区进行患者导航。(E.Calhoun，PI)2)乳腺癌筛查干预措施，以改善服务不足的少数族裔妇女遵守癌症控制指南的情况(K.Hoskins，PI)；按种族/民族划分的DNA甲基化和区分癌症侵袭性(G.Rauscher，Pi)和四个核心：管理(R.Warneke(联系人)和E.Calhoun(共同核心领导人)；政策和传播(C.Ferrans，CL)；数据管理和评估(T.Johnson，CL)和培训与职业发展(F Davis，CL)我们持续的长期愿景是测试和建立干预措施，通过多层次和多学科的人口健康战略解决人口健康差距的决定因素。为了实现这一目标，我们将：1)进行研究，以影响管理乳房X光检查和乳腺癌治疗的政策，并确保平等获得乳腺癌护理标准，无论在哪里提供以及谁提出要求。2)使贫穷和得不到充分服务的妇女认识到需要以确保最佳结果的方式获得护理。3)从跨学科研究角度对青年学者进行健康差距研究方面的培训。