Molecular and Cellular Biology & Biochemistry and Structural Biology Graduate Tra

分子和细胞生物学

• 批准号: 8694046
• 负责人: Robert S. Haltiwanger
• 金额: $ 20.05万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8694046
• 关键词: Biochemistry; Molecular and Cellular Biology; structural biology

DESCRIPTION (provided by applicant): The goal of the Molecular, Cellular, and Structural Biology (MCSB) Training Program is to provide outstanding pre-doctoral training on a wide variety of topics involving basic biological and biomedical processes at the molecular and cellular level. The training in biochemistry, molecular biology, cell biology, and structural bioloy emphasized in this program will help to generate the next generation of basic scientists in this country. The training program offers a multidisciplinary course of study leading to the Ph.D. degree and provides students with the opportunity to select one of four specializations: Biochemistry and Molecular Biology; Cellular and Developmental Biology; Immunology and Pathology; and Structural Biology. During the first year all students enroll in core courses including Graduate Biochemistry, Molecular Genetics, and/or Graduate Cell Biology. Depending on their academic specialization future courses include Structural Biology and Spectroscopy, Cell and Developmental Biology, or Immunology and General Pathology. Students also initially receive training to critically evaluate original research articles in a Journal Club. In addition, hey gain teaching experience as Teaching Assistants in undergraduate biology laboratories. In subsequent years they gain additional experience in oral presentation by giving 30-minute seminars on their research to the entire graduate program. Three to four laboratory training experiences, or rotations, serve to help the student to select a mentor for her/his thesis research at completion of her/his first academic year. The MCSB program is quite diverse, crossing departmental and institutional boundaries to offer thesis research training in 72 different mentored laboratories at three institutions: Stony Brook University, Brookhaven National Laboratory, or Cold Spring Harbor Laboratory. There are currently 101 students in the program with approximately 20 admissions per year. Four of the top first year students will be selected by the Executive Committee to be supported as NIH predoctoral trainees for their second year. Assuming the student continues to progress well (as determined by course work, qualifying exam results, and recommendation of the mentor) support can be renewed for their third year. Thus, a total of eight students will be supported each year (four second-year students, and four third-year students). Second year students are required to pass a written qualifying exam. Subsequently, the students present yearly reports on their research progress in a seminar forum to other graduate students, postdoctoral fellows, and faculty. In the third year of the program students prepare a proposal on their intended research project and defend the proposal before a faculty committee. Following successful defense of the proposal, students advance to candidacy and the faculty thesis committee monitors the students' progress until successful completion of the project and defense of a written doctoral thesis.

描述(由申请人提供)：分子、细胞和结构生物学(MCSB)培训计划的目标是在分子和细胞层面上提供涉及基本生物和生物医学过程的各种主题的杰出博士前培训。该计划强调的生物化学、分子生物学、细胞生物学和结构生物学方面的培训将有助于培养这个国家的下一代基础科学家。该培训计划提供通往博士学位的多学科学习课程，并为学生提供选择四个专业之一的机会：生物化学和分子生物学；细胞和发育生物学；免疫学和病理学；以及结构生物学。在第一年，所有学生都要学习核心课程，包括研究生生物化学、分子遗传学和/或研究生细胞生物学。根据他们的学术专业，未来的课程包括结构生物学和光谱学，细胞和发育生物学，或免疫学和普通病理学。学生最初还会在期刊俱乐部接受对原创研究文章进行批判性评估的培训。此外，还获得了本科生物实验室助教的教学经验。在接下来的几年里，他们通过在整个研究生项目中举办30分钟的研讨会来获得更多的口头陈述经验。三到四次实验室培训经验，或轮换，帮助学生为她/他的论文研究选择导师 在她/他的第一个学年结束时。MCSB项目非常多样化，跨越部门和机构的界限，在三个机构的72个不同的指导实验室提供论文研究培训：石溪大学、布鲁克海文国家实验室或冷泉港实验室。该项目目前有101名学生，每年约有20名学生入学。四名顶尖的一年级学生将被执行委员会挑选出来，作为NIH博士前实习生在他们第二年的支持。假设学生继续进步良好(根据课程作业、合格考试成绩和导师的推荐来确定)，则可以在他们的第三年续签支持。因此，每年将总共资助八名学生(四名二年级学生和四名三年级学生)。二年级的学生需要通过一次笔试。随后，学生们在研讨会论坛上向其他研究生、博士后研究员和教职员工报告他们的研究进展。在项目的第三年，学生们准备一份关于他们想要的研究项目的提案，并在教员委员会面前为该提案辩护。在成功为提案辩护后，学生进入候选人资格，教师论文委员会监督学生的进展，直到成功完成项目并为一篇书面博士论文辩护。