FASEB SRC on

FASEB SRC 开启

• 批准号: 8719401
• 负责人: Li-Na Wei
• 金额: $ 4万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-07 至 2015-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8719401
• 关键词: Address; Alzheimer' s Disease; American; Award; Biochemical; Biological Process; Biology; Carotenoids; Chemicals; Chicago; Clinical; Collaborations; Databases; Development; Diabetes Mellitus; Discipline; Disease; Embryonic Development; Enzymatic Biochemistry; Fostering; Funding; Goals; Health; Human; Illinois; Immunity; Immunologist; Individual; International; Investigation; Malignant Neoplasms; Metabolic Diseases; Metabolism; Molecular; Neuro-Ocular System; Nutritional; Physiological; Postdoctoral Fellow; Request for Applications; Research; Research Activity; Research Personnel; Research Project Grants; Retinoids; Role; Scientist; Series; Signal Transduction; Skin Cancer; Societies; Stem cells; Structural Biologist; Techniques; Technology; Therapeutic; United States National Institutes of Health; Vision; Vitamin A; Work; abstracting; bench to bedside; career; cell type; disorder prevention; graduate student; insight; meetings; nervous system disorder; novel therapeutics; nutrition; posters; prevent; public health relevance; stem cell biology; symposium

DESCRIPTION (provided by applicant): This application requests partial support for the 17th Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference on Retinoids to be held at Itasca, Illinois on June 1-6, 2014. This bi- annual research conference has been very well attended (ranging from 100 to 200 attendees over the past 30 years) and remains the sole major national and international conference that addresses the full spectrum of retinoid biology. While the mechanisms of action and the biological functions of retinoids have been intensively studied, there is an increasing need in understanding and applying retinoids in human nutrition and diseases. Currently, a great deal of ongoing research activity is supported by the NIH (the NIH RePORT database indicates that there are currently 1,460 NIH funded individual research grants involving retinoid/vitamin A biology). The 2014 conference will start with a new "Round Table" panel providing a holistic and historical view by several senior investigators in the field. This will be followed by 8 symposia, 2 traditional poste sessions, and one new "Poster Award" in conjunction with a new "Meet the Expert" session to close the meeting. The goal is to foster the exchange of new research findings. In particular, we aim to encourage new/young investigators meeting and networking with senior investigators in this field, and facilitate the inclusion of new insights/ideas/techniques from scientists and clinicians in other related fields. The main topics to be addressed at the conference include both basic and translational fronts of retinoid biology: (1) retinoid metabolism; (2) retinoid enzymology; (3) retinoid signaling; (4) retinoids in development and stem cell biology; (5) retinoids in disease I - cancers; (6) retinoids in disease II - immunity and metabolism; (7) retinoids in disease III - eyes and the nervous systems; (8) retinoids and carotenoid chemical biology. The overall goal is to bring together a group of investigators (senior scientists, mid-career scientists, junior scientists, postdoctoral fellows, and graduate students) who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, vision researchers, stem cell biologists, biophysicists, structural biologists, immunologists, chemists, and clinicians) to present and discuss their newest research findings that share a common focus on the retinoids. This conference will provide a forum for critical review of recent research and incorporation of newly developed ideas and technologies into translational fronts of this classical topic. This will allow new investigations to provide needed insight into the applications of retinoids in preventing disease and maintaining health and in developing new therapeutics, and facilitate collaborations among basic scientists and clinicians.

描述（由申请人提供）：本申请要求部分支持将于2014年6月1日至6日在伊利诺伊州伊塔斯卡举行的第17届美国实验生物学学会联合会（FASEB）类维生素a夏季研究会议。这个两年一次的研究会议参加人数非常多（在过去的30年里，参加人数从100到200人不等），并且仍然是唯一一个涉及类视黄醇生物学全谱的主要国家和国际会议。在类维生素a的作用机制和生物学功能被深入研究的同时，对类维生素a在人类营养和疾病中的理解和应用的需求日益增加。目前，大量正在进行的研究活动是由美国国立卫生研究院支持的（美国国立卫生研究院报告数据库表明，目前有1460个美国国立卫生研究院资助的个人研究经费涉及类视黄醇/维生素a生物学）。2014年的会议将以一个新的“圆桌会议”小组开始，由该领域的几位高级研究人员提供全面和历史的观点。随后将举行8场专题讨论会，2场传统的专题讨论会，以及一场新的“海报奖”，同时还有一场新的“专家见面会”来结束会议。其目标是促进新的研究成果的交流。特别是，我们的目标是鼓励新/年轻的研究者与该领域的资深研究者会面和交流，并促进其他相关领域的科学家和临床医生的新见解/想法/技术的融合。会议将讨论的主要议题包括类维甲酸生物学的基础和转化前沿：(1)类维甲酸代谢；(2)类维甲酸酶学；(3)类视黄醛信号；(4)类维生素a在发育和干细胞生物学中的作用；(5)类维生素a在疾病I -癌症中的作用；(6)类维生素a在疾病II -免疫和代谢；(7)类维生素a疾病III -眼睛和神经系统；(8)类维生素a和类胡萝卜素化学生物学。总体目标是汇集一群来自不同学科(生物化学家、分子生物学家、营养科学家、癌症研究人员、视觉研究人员、干细胞生物学家、生物物理学家、结构生物学家、免疫学家、化学家、和临床医生)来展示和讨论他们最新的研究发现，这些发现都集中在类维生素a上。本次会议将提供一个论坛，对最近的研究进行批判性审查，并将新开发的思想和技术纳入这一经典主题的转化前沿。这将使新的研究能够为类维生素a在预防疾病和维持健康以及开发新疗法方面的应用提供所需的见解，并促进基础科学家和临床医生之间的合作。