Spillover effects of water, sanitation, and hygiene interventions on child health
Spillover effects of water, sanitation, and hygiene interventions on child health
批准号:
8702490
负责人:
JOHN M COLFORD
金额:
$20.97万
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-05-16 至 2016-04-30
关键词:
AccountingAffectAgeAge-MonthsBackBangladeshCaregiversCessation of lifeChildChild DevelopmentChild health careClinical Trials DesignCommunicable DiseasesDataData CollectionDeveloping CountriesDiarrheaDisciplineEconomicsEffectiveness of InterventionsEnrollmentEnsureExperimental DesignsFoundationsFundingFutureHandwashingHealthHealth BenefitHealth ResourcesHelminthsHouseholdHygieneIndividualInfectionInterventionIntestinal parasiteKenyaKnowledgeLeadLifeLinkLiteratureLow PrevalenceMeasurementMeasuresMethodologyMethodsModelingNatureNeighborhoodsNewborn InfantOnly ChildOutcomeOutcome MeasurePopulationPopulation InterventionPositioning AttributeRandomizedRandomized Controlled TrialsReportingResource AllocationRuralRural PopulationSanitationScienceSoapsSoilTestingVaccinesWaterWorkWorld Health Organizationarmbasecohortcost effectivenessdesigndisability-adjusted life yearsdisease transmissionenteric pathogenfollow-upimprovedinnovationintervention effectmathematical modelmemberpathogenpreventprimary outcomepublic health relevancerandomized trialrespiratorysocialtransmission processuptakewater treatment
中文摘要
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英文摘要
DESCRIPTION (provided by applicant): A substantial body of evidence suggests that water, sanitation, and hygiene (WASH) interventions can effectively reduce diarrheal illness and other infectious diseases. While numerous studies have measured effects on children receiving WASH interventions, no studies have measured their effects ("spillovers") on non-recipients who live adjacent to intervention recipients. Spillovers are important to understand because, when present, the estimated effects and cost effectiveness of interventions will be biased downwards. Although a rich, model-based literature describes spillovers of infectious disease interventions, few studies have measured spillovers empirically. We propose a randomized study to quantitate spillovers from WASH interventions. Our results will inform prioritization of interventions and guide allocation of public funds. Specific aim: We propose to measure spillovers of water, sanitation, and hygiene interventions in an existing, large, rigorously designed trial: the WASH Benefits trial. Funded by the Bill & Melinda Gates Foundation, this trial aims to measure the individual and combined effects of water, sanitation, and hygiene interventions on child health and development. It is a cluster-randomized, controlled trial with si treatment arms and a double- sized control arm carried out in rural Bangladesh. WASH Benefits is the ideal platform upon which to design a study of spillovers because of its rigorous design, it large size (N=5,760 newborns), and the range of individual interventions it evaluates. We hypothesize that children who live in close proximity to compounds that receive a combined sanitation, hand washing, and water treatment intervention--compared to children who live in close proximity to control compounds (no intervention)--will have: 1) lower prevalence of diarrhea, 2) lower prevalence and intensity of infection of soil transmitted helminths, and 3) lower prevalence of respiratory illness. Methods: We will collect additional data from the existing
combined intervention (sanitation+handwashing +water) and control arms of the WASH Benefits trial. For each WASH Benefits household, we will locate the nearest household with children 0-59 months of age that are not enrolled in WASH Benefits and collect data in that household. Our primary outcomes are caregiver-reported 7-day diarrhea and respiratory illness among children 0-59 months as well as soil transmitted helminth infection among children 0-59 months (the same age as the WASH Benefits cohort). Our findings will document either the presence or absence of spillovers of WASH interventions. Innovation: This will be among the first studies to empirically measure spillover effects with an experimental design, and it will be the first study t do so for WASH interventions. Our innovative and interdisciplinary design along with our findings will contribute to methodology in multiple disciplines (e.g. economics, political science)
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会议论文
Spillover effects of water, sanitation, and hygiene interventions on child health
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批准号:8849933
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项目类别:
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资助金额:$15.48万
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财政年份:2014
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负责人:JOHN M COLFORD
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依托单位:
Effects of sanitation on pathogen transmission and child health in Bangladesh
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批准号:9085114
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资助金额:$53.01万
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负责人:JOHN M COLFORD
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Effects of sanitation on pathogen transmission and child health in Bangladesh
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负责人:JOHN M COLFORD
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依托单位:
Child health risks attributable to swimming in contaminated water at beaches in t
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资助金额:$7.61万
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负责人:JOHN M COLFORD
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依托单位:
Child health risks attributable to swimming in contaminated water at beaches in t
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批准号:8493229
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项目类别:
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资助金额:$7.82万
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财政年份:2013
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负责人:JOHN M COLFORD
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依托单位:
Indicators of Recreational Water Contamination and Illness
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批准号:7100352
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项目类别:
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资助金额:$47.7万
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财政年份:2006
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负责人:JOHN M COLFORD
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依托单位:
Indicators of Recreational Water Contamination and Illness
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批准号:7391313
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项目类别:
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资助金额:$40.93万
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财政年份:2006
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负责人:JOHN M COLFORD
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依托单位:
Indicators of Recreational Water Contamination and Illness
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批准号:7590313
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项目类别:
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资助金额:$41.36万
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财政年份:2006
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负责人:JOHN M COLFORD
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依托单位:
Indicators of Recreational Water Contamination and Illness
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批准号:7796538
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项目类别:
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资助金额:$35.1万
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财政年份:2006
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负责人:JOHN M COLFORD
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依托单位:
Indicators of Recreational Water Contamination and Illness
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批准号:7252448
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项目类别:
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资助金额:$41.2万
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财政年份:2006
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负责人:JOHN M COLFORD
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依托单位:
Solar Water Disinfection: Randomized Intervention Trial
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项目类别:
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财政年份:2002
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负责人:JOHN M COLFORD
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依托单位:
Solar Water Disinfection: Randomized Intervention Trial
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项目类别:
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资助金额:$5.76万
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财政年份:2002
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负责人:JOHN M COLFORD
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依托单位:
Solar Water Disinfection: Randomized Intervention Trial
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项目类别:
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资助金额:$11.56万
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财政年份:2002
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负责人:JOHN M COLFORD
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依托单位:
Solar Water Disinfection: Randomized Intervention Trial
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批准号:6765926
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项目类别:
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资助金额:$57.8万
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财政年份:2002
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负责人:JOHN M COLFORD
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依托单位:
Solar Water Disinfection: Randomized Intervention Trial
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项目类别:
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资助金额:$57.19万
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财政年份:2002
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负责人:JOHN M COLFORD
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依托单位:
RANDOMIZED TRIAL OF TAPWATER TREATMENT IN THE ELDERLY
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项目类别:
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资助金额:$59.64万
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财政年份:2000
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负责人:JOHN M COLFORD
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依托单位:
RANDOMIZED TRIAL OF TAPWATER TREATMENT IN THE ELDERLY
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项目类别:
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资助金额:$55.73万
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负责人:JOHN M COLFORD
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依托单位:
RANDOMIZED TRIAL OF TAPWATER TREATMENT IN THE ELDERLY
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批准号:6737472
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项目类别:
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资助金额:$52.32万
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财政年份:2000
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负责人:JOHN M COLFORD
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依托单位:
RANDOMIZED TRIAL OF TAPWATER TREATMENT IN THE ELDERLY
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批准号:6509626
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项目类别:
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资助金额:$59.55万
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财政年份:2000
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负责人:JOHN M COLFORD
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依托单位:
RANDOMIZED TRIAL OF TAPWATER TREATMENT IN THE ELDERLY
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项目类别:
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依托单位:
海外基金