2014 Parkinson Study Group Symposium and Training

 描述(由申请者提供)：拟议的会议项目以帕金森研究小组(PSG)的年度临床研究研讨会和相关的年度会议活动为中心，将促进对早期研究人员的教育和培训，以确保继续进行最高质量的转化和临床研究，以改进帕金森氏症和相关神经疾病的治疗。该项目目标将通过两个具体目标(SA)来实现。在SA#1中，PSG将于2014年9月19日(星期五)在密苏里州圣路易斯市与亨廷顿研究小组(HSG)、肌萎缩症研究小组(DSG)、抽动症研究小组(TSSG)、协作性共济失调小组(CAG)和震颤研究小组(TRG)合作举办“第28届帕金森氏病和其他运动障碍的病因、发病机制和治疗年度研讨会”。同行评议的节目包括平台和海报演示，以现场直播的形式进行，观众参与。研讨会将包括运动障碍的当前问题，重点是疾病修改的主题演讲，重点是新的治疗方法和同行评议的平台，以及关于运动障碍的海报演示，包括帕金森病(PD)、亨廷顿病、Dystonia、共济失调和震颤。主题旨在交流最新的研究进展，包括运动障碍领域的新的药理学和非药理学治疗选择，从而加强患者护理。临床实践中需要解决的差距是与翻译和临床研究有关的未得到满足的需求，以及对受运动障碍影响的患者和家庭的护理和治疗。SA#2旨在为早期临床研究人员提供运动障碍培训，并为PD临床研究提供多方面的实用指导。除了研讨会外，入选的初级研究人员还将参加几项新颖和互动的教育研究活动，其中包括：a)与帕金森病基金会合作伙伴(帕金森研究倡导者)计划的经验丰富的患者倡导者直接交流合作策略，以通过纳入患者的观点来改进临床研究；b)PSG指导委员会的初级研究员职业发展研讨会；c)NINDS支持的STRATE-PD3研究的研究员迎新会议，这是一项针对候选疾病修改神经疗法的56个地点的随机临床试验，为临床试验开发的基本原理和机制提供了有价值的介绍。完成该项目的初级研究人员将得到更好的准备，并有动力追求临床神经学的职业和研究。

 DESCRIPTION (provided by applicant): The proposed conference project, centered on the annual clinical research symposium of the Parkinson Study Group (PSG) and associated annual meeting activities, will foster the education and training of early stage investigators to ensure that the highest quality translational and clinical research continues to be conducted toward improved therapy for Parkinson's and related neurological diseases. This project goal will be achieved through two specific aims (SAs). In SA #1, the PSG will present the "28th Annual Symposium on Etiology, Pathogenesis, and Treatment of Parkinson's Disease and Other Movement Disorders" in collaboration with the Huntington Study Group (HSG), Dystonia Study Group (DSG), Tourette Syndrome Study Group (TSSG), Cooperative Ataxia Group (CAG), and Tremor Research Group (TRG) on Friday, September 19, 2014 in St. Louis, Missouri. The peer-reviewed program includes both platform and poster presentations in a live format with audience participation. The symposium will consist of current issues in movement disorders with keynote talks on disease modification focusing on new therapies and peer-reviewed platform and poster presentations on movement disorders including Parkinson disease (PD), Huntington disease, Dystonia, Ataxia, and Tremor. Topics are designed to communicate recent research advances, including new pharmacological and non-pharmacological treatment options in the field of movement disorders thereby enhancing patient care. The gaps in clinical practice to address are the unmet needs pertaining to the translational and clinical research, along with the care and treatment of patients and families affected by movement disorders. SA #2 is designed to provide early-stage clinical investigators with movement disorders training and a multi-faceted practical orientation to PD clinical research. The selected junior investigators will participate i several novel and interactive, educational research activities in addition to the symposium, including a) direct exchange with experienced patient advocates of the Parkinson's Disease Foundation's PAIR (Parkinson's Advocates in Research) program over collaborative strategies to improve clinical research by incorporating patient perspectives; b) the PSG Mentoring Committee's junior investigator career development workshop; c) the investigator orientation meeting of the NINDS-supported STEADY-PD3 study, a 56-site randomized clinical trial of a candidate disease-modifying neurotherapeutic, offering a valuable introduction to the rationale and mechanics underlying clinical trial development. Junior investigators completing participation in the project will be substantially better prepared and motivated to pursue careers and studies in clinical neurology.