2019 Parkinson Study Group Symposium and Training

2019年帕金森研究组研讨会及培训

• 批准号: 9890023
• 负责人: MICHAEL A SCHWARZSCHILD
• 金额: $ 2.5万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9890023
• 关键词: Address; Advocate; Applications Grants; Ataxia; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Collaborations; Development; Disease; Dystonia; Education; Educational Activities; Educational workshop; Effectiveness; Ensure; Etiology; Faculty; Fostering; Foundational Skills; Foundations; Future; Genetic; Gilles de la Tourette syndrome; Goals; Grant; Human; Huntington Disease; Inherited; Investments; Knowledge; LRRK2 gene; Learning; Mentors; Methodology; Movement Disorders; Mutation; Neurobiology; Neurodegenerative Disorders; Neurology; Parkinson Disease; Participant; Pathogenesis; Patient Care; Patients; Peer Review; Pharmacology; Phenotype; Pilot Projects; Program Reviews; Research; Research Activity; Research Methodology; Research Personnel; Research Project Grants; Scientist; Series; Site; Study Section; Therapeutic; Training; Training and Education; Translational Research; Tremor; Writing; career; career development; clinical development; data mining; design; experience; genetic epidemiology; improved; insight; meetings; mobile computing; nervous system disorder; neuroimaging; novel; patient oriented; personalized medicine; posters; programs; research study; skills; statistics; symposium; therapeutic development

Abstract The proposed three-year conference project, centered on the annual clinical research symposium of the Parkinson Study Group (PSG) and associated annual meeting activities, will foster the education and training of early stage investigators to ensure that the highest quality translational and clinical research continues to be conducted toward improved therapy for Parkinson's and related neurological disease. This project goal will be achieved through two specific aims (SAs). In SA #1, the PSG will present its “32nd Annual Symposium on the Etiology, Pathogenesis, and Treatment of Parkinson's Disease and Other Movement Disorders” in collaboration with the Huntington Study Group (HSG), Dystonia Study Group (DSG), Tourette Syndrome Study Group (TSSG), Cooperative Ataxia Group (CAG), and Tremor Research Group (TRG) on Saturday, April 6, 2019 in Phoenix, AZ, and the 33rd and 34th symposia annually thereafter. The peer-reviewed program includes both platform and poster presentations in a live format with audience participation. The symposia themes will authoritatively address major challenges and opportunities in pursuit of improved treatment for people with Parkinson's and other neurodegenerative diseases, with keynote talks conveying complementary neurobiological, clinical development and patient perspectives. The 2019 Symposium will cover the revolutionary impact of PD genetics, and GBA and LRRK2 mutations in particularly, on PD therapeutics development. SA #2 is designed to provide early-stage clinical investigators with movement disorders training a multi-faceted practical orientation to PD clinical research. The selected junior investigators will participate in several novel and interactive, educational research activities in addition to the symposium, including a) direct exchange with experienced patient advocates of the Parkinson's Foundation's PAIR (Parkinson's Advocates in Research) program to learn how patient input can benefit their research, and b) the PSG Mentoring Committee's junior investigator skills workshop with annually rotating themes spanning clinical research project development, grant proposal writing, and emerging research methodologies. Junior investigators completing participation in the project will be substantially better prepared and motivated to pursue careers and rigorous studies in clinical neurology.

抽象的 拟议的三年会议项目以年度临床研究研讨会为中心 帕金森研究小组（PSG）和相关的年度会议活动将促进教育和 培训早期研究人员，以确保最高质量的转化和临床研究 继续进行改进帕金森氏症和相关神经疾病的治疗。 这个项目目标将通过两个特定目标（SAS）实现。在SA＃1中，PSG将展示其 “第32届关于帕金森氏病的病因，发病机理和治疗的年度研讨会 其他运动障碍”与亨廷顿研究小组（HSG）合作，肌张力障碍研究 组（DSG），图雷特综合征研究小组（TSSG），合作社共济失调小组（CAG）和震颤 研究小组（TRG）于2019年4月6日（星期六 此后每年。同行评审的程序在现场中包括平台和海报演示文稿 与观众参与的格式。研讨会主题将对重大挑战进行权威地解决 以及寻求改进帕金森氏症和其他人的治疗的机会 神经退行性疾病，主题演讲传达了完整的神经生物学，临床 发展和患者的观点。 2019年研讨会将涵盖PD的革命性影响 遗传学，尤其是GBA和LRRK2突变，关于PD治疗的开发。 SA＃2是 旨在为早期临床研究人员提供运动障碍训练一个多方面的运动障碍 PD临床研究的实际取向。选定的初级调查人员将参加几个 除了研讨会之外，还包括新颖和互动的教育研究活动，包括a）直接 与经验丰富的患者倡导者交流帕金森基金会的一对 研究计划的倡导者）了解患者的投入如何使他们的研究受益，b）PSG 指导委员会的初级调查员技能讲习班与年度旋转主题跨越临床 研究项目开发，赠款提案写作和新兴研究方法。初级 完成参与该项目的调查人员将做好更好的准备和融合 从事临床神经病学的职业和严格研究。