Administrative and Bioinformatics Core

行政核心(核心A)将指导和协调对以下活动作出贡献的几个主要领域 作为杀菌剂的直肠灌肠(DREAM)计划的发展，其总体目标是开发一种 单剂替诺福韦前体药物灌肠可提供一周的保护，防止以下患者感染艾滋病毒 无保护的接受性肛交。这些活动包括(1)对整个 包括所有项目和核心的计划，(2)提供计划的财务监督，(3)充当主要角色 与NIAID/DAIDS指定的项目官员联络，负责综合 艾滋病毒杀微生物剂临床前/临床方案和生物医学预防U19方案，(4)协调 每月召开指导委员会电话会议，并在 及时，(5)组织IP/CP年度会议，(5)与NIAID/DAIDS合作，建立和 为科学咨询小组提供后勤支持，并(6)进行网站维护， 教育、出版援助、图书馆维护和一般行政支助。核心将链接 不同的项目负责人和计划，以及整合每个项目和 确保项目负责人之间的沟通。特别委员会，由首席调查员和每个 项目领导/助理-领导、核心领导/助理领导和选择关键人员将是中心 确保项目、项目现场和核心之间的沟通的机制。行政核心 还将为常委会编写一年两次的内部进度报告。这些信息将提供给感兴趣的密钥 美国国立卫生研究院的科学咨询小组(SAP)。

The Administrative Core (Core A) will direct and coordinate several major areas contributing to the activities of the Development of Rectal Enema as Microbicide (DREAM) Program whose overall goal it is to develop a single dose tenofovir prodrug enema to provide one week of protection from HIV infection following unprotected receptive anal intercourse. These activities include (1) administrative oversight of the entire program including all Projects and Cores, (2) providing financial oversight of the program, (3) act as primary liaison with the NIAID/DAIDS appointed Program Officer with responsibility for the Integrated Preclinical/Clinical Program for HIV Microbicides and Biomedical Prevention U19 Program, (4) coordinate the monthly conference calls for the Steering Committee (SC) and disseminate agendas / meeting minutes in a timely fashion, (5) organize the annual IP/CP meeting, (5) in collaboration with NIAID/DAIDS, establish and provide logistical support for a Scientific Advisory Panel facilitation, and (6) undertake website maintenance, education, publication assistance, library maintenance, and general administrative support. The Core will link the various project leaders and programs as well as integrate the related milestones of each project and ensuring communication between project leaders. The SC, composed of the Principal Investigator and each Project Leader/Associate-Leader, Core Leader/Associate Leader, and select key personnel, will be the central mechanism in assuring communication between Projects, Project sites, and Cores. The Administrative Core will also produce twice-yearly internal progress reports for the SC. These will be available to interested key personnel and the NIH's Scientific Advisory Panel (SAP).