Administrative and Bioinformatics Core

行政和生物信息学核心

• 批准号: 8768692
• 负责人: Peter A Anton
• 金额: $ 28.51万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8768692
• 关键词: Accountability; Adherence; Adhesives; Anus; Area; Bioinformatics; Clinical; Collaborations; Collection; Committee Membership; Communication; Communities; Data; Data Reporting; Database Management Systems; Development; Development Plans; Documentation; Dose; Early Diagnosis; Education; Ensure; Ethics; Financial Support; Fostering; Foundations; Goals; Group Meetings; HIV; HIV Infections; Health Insurance Portability and Accountability Act; Human Resources; Informatics; Internet; Leadership; Learning; Libraries; Link; Maintenance; Management Audit; Monitor; National Institute of Allergy and Infectious Disease; Play; Policies; Prevention; Principal Investigator; Process; Prodrugs; Progress Reports; Publications; Recurrence; Reporting; Research Infrastructure; Resources; Role; Running; Site; Strategic Planning; Structure; System; Teleconferences; Tenofovir; Time; TimeLine; United States National Institutes of Health; Update; abstracting; biomedical informatics; data management; enema administration; experience; flexibility; interest; meetings; microbicide; operation; pre-clinical; programs; prospective; rectal; rectal microbicide; repository; symposium; web site

The Administrative Core (Core A) will direct and coordinate several major areas contributing to the activities of the Development of Rectal Enema as Microbicide (DREAM) Program whose overall goal it is to develop a single dose tenofovir prodrug enema to provide one week of protection from HIV infection following unprotected receptive anal intercourse. These activities include (1) administrative oversight of the entire program including all Projects and Cores, (2) providing financial oversight of the program, (3) act as primary liaison with the NIAID/DAIDS appointed Program Officer with responsibility for the Integrated Preclinical/Clinical Program for HIV Microbicides and Biomedical Prevention U19 Program, (4) coordinate the monthly conference calls for the Steering Committee (SC) and disseminate agendas / meeting minutes in a timely fashion, (5) organize the annual IP/CP meeting, (5) in collaboration with NIAID/DAIDS, establish and provide logistical support for a Scientific Advisory Panel facilitation, and (6) undertake website maintenance, education, publication assistance, library maintenance, and general administrative support. The Core will link the various project leaders and programs as well as integrate the related milestones of each project and ensuring communication between project leaders. The SC, composed of the Principal Investigator and each Project Leader/Associate-Leader, Core Leader/Associate Leader, and select key personnel, will be the central mechanism in assuring communication between Projects, Project sites, and Cores. The Administrative Core will also produce twice-yearly internal progress reports for the SC. These will be available to interested key personnel and the NIH's Scientific Advisory Panel (SAP).

行政核心（核心A）将指导和协调促进以下活动的几个主要领域 直肠灌肠作为杀微生物剂的发展（梦想）计划，其总体目标是开发一种 单剂量替诺福韦前体药物灌肠剂提供一周的保护，从艾滋病毒感染后， 无保护的肛交这些活动包括：（1）对整个 计划，包括所有项目和核心，（2）提供计划的财务监督，（3）作为主要的 与NIAID/DAIDS任命的负责综合 HIV杀微生物剂和生物医学预防U19计划的临床前/临床计划，（4）协调 每月召开指导委员会（SC）会议，并以 及时，（5）组织年度IP/CP会议，（5）与NIAID/DAIDS合作， 为科学咨询小组提供后勤支持，以及（6）进行网站维护， 教育、出版援助、图书馆维护和一般行政支助。核心将连接 各种项目负责人和项目，并整合每个项目的相关里程碑， 确保项目负责人之间的沟通。SC由主要研究者组成， 项目负责人/副负责人、核心负责人/副负责人和选定的关键人员将是 确保项目、项目地点和核心之间沟通的机制。行政核心 每年还将为SC编写两次内部进度报告。这些报告将提供给感兴趣的关键 NIH的科学顾问小组（SAP）。