2014 Neurobiology of Brain Disorders Gordon Research Conference & Gordon Research

2014年脑部疾病神经生物学戈登研究会议

• 批准号: 8714546
• 负责人: Joachim J Herz
• 金额: $ 5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-03-15 至 2015-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8714546
• 关键词: Aging; Alzheimer' s Disease; Area; Attention; Autophagocytosis; Biochemistry; Biology; Biomedical Research; Brain; Brain Diseases; Cause of Death; Cellular biology; Communities; Data; Developed Countries; Development; Discipline; Disease; Elderly; Electrophysiology (science); Faculty; Functional disorder; Future; Genetic; Goals; Golf; Human; Imaging technology; International; Longevity; Lysosomes; Maps; Melia; Mentors; Minority; Molecular; Nerve Degeneration; Nervous system structure; Neurobiology; Neurodegenerative Disorders; Neurosciences; Neurosciences Research; Oral; Participant; Physiological; Postdoctoral Fellow; Prevalence; Process; Property; Public Health; RNA; Request for Applications; Research; Research Personnel; Resort; Risk Factors; Scientist; Series; Spain; Students; Synapses; Syndrome; Time; Translational Research; Woman; Work; age related; age related neurodegeneration; base; graduate student; interdisciplinary collaboration; interest; lipid metabolism; meetings; member; neglect; nervous system disorder; network dysfunction; novel therapeutics; planetary Atmosphere; posters; protein aggregation; protein misfolding; public health relevance; symposium; translational approach

DESCRIPTION (provided by applicant): This application requests partial support for a meeting on the "Neurobiology of Brain Disorders", this time with a special emphasis on the impact of aging on the dysfunction of the nervous system, as part of a Gordon Research Conference series to be held at Melia Golf Vichy Catalan Resort near Girona, Spain from July 27- August 1, 2014. The Specific Aims of this GRC are to bring together leading scientists who are at the forefront of the field of neurodegenerative and aging-related disorders of the nervous system to present and discuss their latest findings and concepts. The Conference will feature a wide range, but related topics that are relevant to common disease mechanisms of different neurodegenerative and aging-related syndromes, such as synaptic dysfunction, autophagy, protein misfolding and aggregation, circuit and network dysfunction, lipid metabolism and lysosome biology, and RNA mechanisms. Invited speakers represent a wide variety of scientific disciplines, including genetics, biochemistry, cell biology, electrophysiology and imaging technology. Every effort will be made to encourage participation of graduate students, postdoctoral fellows and junior faculty members as well as women and members of minority communities. The Conference will provide opportunities for junior scientists to present their work in the poster sessions and to interact informally with leaders in the field. In addition, short tals will be selected from the submitted posters, so junior scientists will have opportunities to participate in oral presentations. The collegial atmosphere and the ample free time in the afternoons and late evenings provide ideal settings for participants from different disciplines to brainstorm and establish interdisciplinary collaborations. The significance of this application is that this GRC will provide a unique forum for the international community working on the neurobiology of brain disorders to come together and discuss the latest advances and the future challenges in the field of neurodegeneration and aging-related disorders of the nervous system. The relevance of this application to public health is that the discussions generated will help define the most pertinent important questions in the field of neurodegenerative diseases in terms of both basic biology and disease mechanisms, which will aid the development of novel therapeutic strategies for these devastating diseases that are major public health problems. The long-term goal of this GRC is to provide a consistent platform for the community to meet regularly (every two years) in order to disseminate the most recent discoveries and to formulate the most important questions concerning the current state of the art research on brain disorders.

描述（由申请人提供）：本申请请求对“脑部疾病的神经生物学”会议提供部分支持，这次会议特别强调衰老对神经系统功能障碍的影响，作为戈登研究会议系列的一部分，将于 2014 年 7 月 27 日至 8 月 1 日在西班牙赫罗纳附近的美利亚高尔夫维希加泰罗尼亚度假村举行。该 GRC 的具体目标是汇集来自以下领域的顶尖科学家： 处于神经退行性和与衰老相关的神经系统疾病领域的前沿，展示和讨论他们的最新发现和概念。会议将讨论与不同神经退行性和衰老相关综合征的常见疾病机制相关的广泛但相关的主题，例如突触功能障碍、自噬、蛋白质错误折叠和聚集、电路和网络功能障碍、脂质代谢和溶酶体生物学以及RNA机制。受邀演讲者代表了广泛的科学学科，包括遗传学、生物化学、细胞生物学、电生理学和成像技术。我们将尽一切努力鼓励研究生、博士后研究员和初级教员以及妇女和少数族裔社区成员的参与。会议将为年轻科学家提供在海报会议上展示其工作并与该领域的领导者进行非正式互动的机会。此外，将从提交的海报中选出短篇小说，以便初级科学家有机会参加口头报告。学院的氛围以及下午和晚上充足的空闲时间为来自不同学科的参与者进行集思广益和建立跨学科合作提供了理想的环境。该申请的意义在于，本次 GRC 将为从事脑部疾病神经生物学研究的国际社会提供一个独特的论坛，让他们齐聚一堂，讨论神经退行性和与衰老相关的神经系统疾病领域的最新进展和未来挑战。该应用与公共卫生的相关性在于，所产生的讨论将有助于在基本生物学和疾病机制方面定义神经退行性疾病领域最相关的重要问题，这将有助于针对这些严重公共卫生问题的破坏性疾病制定新的治疗策略。该 GRC 的长期目标是为社区提供一个定期（每两年）举行会议的一致平台，以传播最新发现并提出有关当前脑部疾病研究最新进展的最重要问题。