2014 Neurobiology of Brain Disorders Gordon Research Conference & Gordon Research

2014年脑部疾病神经生物学戈登研究会议

• 批准号: 8714546
• 负责人: Joachim J Herz
• 金额: $ 5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-03-15 至 2015-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8714546
• 关键词: Aging; Alzheimer' s Disease; Area; Attention; Autophagocytosis; Biochemistry; Biology; Biomedical Research; Brain; Brain Diseases; Cause of Death; Cellular biology; Communities; Data; Developed Countries; Development; Discipline; Disease; Elderly; Electrophysiology (science); Faculty; Functional disorder; Future; Genetic; Goals; Golf; Human; Imaging technology; International; Longevity; Lysosomes; Maps; Melia; Mentors; Minority; Molecular; Nerve Degeneration; Nervous system structure; Neurobiology; Neurodegenerative Disorders; Neurosciences; Neurosciences Research; Oral; Participant; Physiological; Postdoctoral Fellow; Prevalence; Process; Property; Public Health; RNA; Request for Applications; Research; Research Personnel; Resort; Risk Factors; Scientist; Series; Spain; Students; Synapses; Syndrome; Time; Translational Research; Woman; Work; age related; age related neurodegeneration; base; graduate student; interdisciplinary collaboration; interest; lipid metabolism; meetings; member; neglect; nervous system disorder; network dysfunction; novel therapeutics; planetary Atmosphere; posters; protein aggregation; protein misfolding; public health relevance; symposium; translational approach

DESCRIPTION (provided by applicant): This application requests partial support for a meeting on the "Neurobiology of Brain Disorders", this time with a special emphasis on the impact of aging on the dysfunction of the nervous system, as part of a Gordon Research Conference series to be held at Melia Golf Vichy Catalan Resort near Girona, Spain from July 27- August 1, 2014. The Specific Aims of this GRC are to bring together leading scientists who are at the forefront of the field of neurodegenerative and aging-related disorders of the nervous system to present and discuss their latest findings and concepts. The Conference will feature a wide range, but related topics that are relevant to common disease mechanisms of different neurodegenerative and aging-related syndromes, such as synaptic dysfunction, autophagy, protein misfolding and aggregation, circuit and network dysfunction, lipid metabolism and lysosome biology, and RNA mechanisms. Invited speakers represent a wide variety of scientific disciplines, including genetics, biochemistry, cell biology, electrophysiology and imaging technology. Every effort will be made to encourage participation of graduate students, postdoctoral fellows and junior faculty members as well as women and members of minority communities. The Conference will provide opportunities for junior scientists to present their work in the poster sessions and to interact informally with leaders in the field. In addition, short tals will be selected from the submitted posters, so junior scientists will have opportunities to participate in oral presentations. The collegial atmosphere and the ample free time in the afternoons and late evenings provide ideal settings for participants from different disciplines to brainstorm and establish interdisciplinary collaborations. The significance of this application is that this GRC will provide a unique forum for the international community working on the neurobiology of brain disorders to come together and discuss the latest advances and the future challenges in the field of neurodegeneration and aging-related disorders of the nervous system. The relevance of this application to public health is that the discussions generated will help define the most pertinent important questions in the field of neurodegenerative diseases in terms of both basic biology and disease mechanisms, which will aid the development of novel therapeutic strategies for these devastating diseases that are major public health problems. The long-term goal of this GRC is to provide a consistent platform for the community to meet regularly (every two years) in order to disseminate the most recent discoveries and to formulate the most important questions concerning the current state of the art research on brain disorders.

申请者描述(申请人提供)：本申请请求部分支持一个关于“大脑疾病的神经生物学”的会议，这次特别强调衰老对神经系统功能障碍的影响，作为Gordon Research Conference系列会议的一部分，该会议将于2014年7月27日至8月1日在西班牙吉罗纳附近的Melia Golf Vichy Catalan Resort举行。GRC的具体目标是将处于神经系统神经退行性和衰老相关疾病领域前沿的领先科学家聚集在一起，介绍和讨论他们的最新发现和概念。会议的专题范围广泛，但与不同神经退行性和衰老相关综合征的常见疾病机制有关，如突触功能障碍、自噬、蛋白质错误折叠和聚集、回路和网络功能障碍、脂代谢和溶酶体生物学，以及RNA机制。被邀请的演讲者代表了各种各样的科学学科，包括遗传学、生物化学、细胞生物学、电生理学和成像技术。将尽一切努力鼓励研究生、博士后研究员和初级教员以及妇女和少数民族社区成员参与。会议将为初级科学家提供机会，在海报会议上介绍他们的工作，并与该领域的领导人进行非正式互动。此外，将从提交的海报中选择简短的总结，因此初级科学家将有机会参与口头陈述。下午和深夜充裕的课余时间，为来自不同学科的参与者集思广益，建立跨学科合作提供了理想的环境。这项申请的意义在于，GRC将为致力于脑疾病神经生物学的国际社会提供一个独特的论坛，让他们齐聚一堂，讨论神经系统神经退化和衰老相关疾病领域的最新进展和未来挑战。这一应用与公共卫生的相关性在于，所产生的讨论将有助于从基本生物学和疾病机制两方面确定神经退行性疾病领域中最相关的重要问题，这将有助于为这些重大公共卫生问题的破坏性疾病制定新的治疗战略。GRC的长期目标是为社区提供一个一致的平台，定期(每两年一次)开会，以传播最新的发现，并制定关于大脑疾病研究现状的最重要问题。