Integrative Cognitive Affective Therapy for Binge Eating Disorder

暴食症的综合认知情感疗法

• 批准号: 8723299
• 负责人: Stephen Arthur Wonderlich
• 金额: $ 23.19万
• 依托单位: SANFORD RESEARCH NORTH
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-23 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8723299
• 关键词: Abstinence; Adherence; Affective; Anxiety; Behavior; Behavioral; Binge Eating; Binge eating disorder; Body mass index; Clinical; Cognition; Cognitive; Cognitive Therapy; DSM-IV; Data; Diagnosis; Diagnostic and Statistical Manual of Mental Disorders; Disease remission; Distress; Eating Behavior; Eating Disorders; Emotions; Evidence based treatment; Frequencies; Hyperphagia; Impairment; Individual; Interview; Laboratories; Maintenance; Measures; Medical; Mental Depression; Modeling; Obesity; Outcome; Outcome Measure; Outpatients; Overweight; Participant; Patient Self-Report; Patients; Pattern; Persons; Physical activity; Pilot Projects; Process; Psychopathology; Psychotherapy; Quality of life; Randomized; Randomized Controlled Trials; Recurrence; Research; Risk Factors; Specific qualifier value; Subgroup; Testing; Treatment Efficacy; Treatment Protocols; Treatment outcome; base; comparative efficacy; depressive symptoms; emotion regulation; follow-up; innovation; public health relevance; secondary outcome; self esteem; self help

DESCRIPTION (provided by applicant): Binge eating disorder (BED) involves recurrent episodes of uncontrolled overeating that cause significant distress and impairment. BED is also considered to be a risk factor for a variety of psychiatric and medical problems, including depression, anxiety, impaired quality of life, obesity, and numerous negative medical outcomes. The present study proposes to compare a new treatment for BED (Integrative Cognitive-Affective Therapy-BED; ICAT-BED) to an evidence based treatment for BED (Cognitive Behavior Therapy-Guided Self- Help; CBTgsh). BED participants will be randomized to one of the two treatment conditions, in which they will receive 17 weeks of outpatient treatment. Participants will be comprehensively assessed at baseline, end of treatment, and 6-month follow-up. In addition, participants will complete Ecological Momentary Assessments (EMA) of eating behavior, emotion, and activity at baseline, end of treatment, and 6-month follow-up. Participants' treatment sessions will be digitally recorded and teams of adherence raters will assess the degree to which clinicians adhered to the treatment protocols. Outcomes will focus on reductions in binge eating behavior and core eating disorder psychopathology, as well as comorbid psychopathology, treatment acceptance, clinical impairment, attrition, body mass index, and physical activity. Hypothesized binge eating maintenance factors including cognitive self-discrepancy will be examined as potential treatment moderators. Data from this project will further clarify the efficacy of ICAT-BED and will provide a test of an underlying conceptual model of BED based on momentary emotion regulation processes.

描述(由申请人提供)：暴饮暴食障碍(床)包括反复发作的不受控制的暴饮暴食，导致严重的痛苦和损害。床也被认为是各种精神和医疗问题的危险因素，包括抑郁、焦虑、生活质量下降、肥胖和许多负面医疗后果。本研究建议将一种新的床疗法(整合认知-情感疗法床；ICAT-床)与一种基于证据的床疗法(认知行为疗法引导的自助；CBTgsh)进行比较。床位参与者将被随机分配到两种治疗条件中的一种，在这两种治疗条件下，他们将接受17周的门诊治疗。参与者将在基线、治疗结束和6个月的随访时进行全面评估。此外，参与者将在基线、治疗结束和6个月的随访时完成对饮食行为、情绪和活动的生态瞬时评估(EMA)。参与者的治疗过程将被数字化记录，依从性评分员团队将评估临床医生遵守治疗方案的程度。结果将集中在暴饮暴食行为和核心饮食障碍精神病理学的减少，以及共病精神病理学、治疗接受度、临床损害、自然减损、体重指数和体力活动的减少。假设的暴饮暴食维持因素，包括认知自我差异，将被视为潜在的治疗调节因素。来自该项目的数据将进一步阐明ICAT-BED的有效性，并将提供基于瞬时情绪调节过程的BED潜在概念模型的测试。