Acquisition of a Siemens Console and Gradients for a 7T MRI/MRS System

项目摘要 这项提议旨在将仅有头部的7T安捷伦/瓦里安MRS扫描仪转换为7T西门子扫描仪 更换控制台和所有射频，以及渐变硬件。这将产生最先进的MRS和MRI 该系统可满足最多60名目前在耶鲁磁报扫描的首席研究人员的研究需求 共振研究中心(MRRC)。此次升级解决了几个问题。首先，安捷伦已经宣布 不再生产7T磁铁，所以如果耶鲁大学要有7T核磁共振，升级这个现有的系统是唯一 前进的道路。其次，由于安捷伦的这一声明，对当前系统的支持将很快 不再可用，如果没有这样的升级，这一昂贵/重要的资源可能会丢失。第三，我们 在耶鲁大学对结构和功能成像能力有很强的需求，空间和 时间分辨率，通过升级这块磁铁，我们可以为大型研究提供这样的能力 耶鲁内外的社区。此外，我们在这两个方面都有几个培训计划 工程学和神经科学将受益于使用这台升级的高场成像仪。我们有 技术专长，与西门子的研究关系，几个异常强大的研究项目， 和用户需求，以证明这项投资是合理的。耶鲁大学已经投入了大量的资源在 在这种情况下，MRRC将提供此次升级成本的50%，这表明 大学提供了这一资源。这将是美国唯一的Head-MRI 68厘米直径7T西门子系统。 世界上还有另外两个--一个在瑞士的卢萨纳，另一个在加拿大的滑铁卢，因此 将是一种独特的资源。

Project Summary This proposal is aimed at converting a head-only 7T Agilent/Varian MRS scanner to a 7T Siemens scanner by replacing the console and all the RF, and gradient hardware. This will yield a state-of-the-art MRS and MRI system to serve the research needs of up to 60 principal investigators that currently scan in the Yale Magnetic Resonance Research Center (MRRC). The upgrade solves several problems. First Agilent has announced it is no longer going to make 7T magnets so if Yale is to have a 7T MRI, upgrading this existing system is the only path forward. Second because of this announcement from Agilent, support for the current system will shortly no longer be available and this expensive/important resource may be lost without such an upgrade. Third we have a strong demand at Yale for both structural and functional imaging capabilities at very high spatial and temporal resolution and by upgrading this magnet we can provide such capabilities to a large research community both within and outside of Yale. Furthermore we have several training programs in both engineering and neuroscience that would benefit from access to this upgraded high field imager. We have the technical expertise, the research relationship with Siemens, several exceptionally strong research programs, and the user needs, to justify this investment. Yale has invested a considerable amount of resources in the MRRC and in this case would provide 50% of the cost of this upgrade demonstrating the importance the university puts on this resource. This would be the only head-MRI 68cm bore 7T Siemens system in the USA. Two others exist in the world - one in Luasanne, Switzerland and the other in Waterloo, Canada and thus this would be a unique resource.