Exercise to prevent depression and anxiety in older Hispanics

锻炼可预防老年西班牙裔人的抑郁和焦虑

• 批准号: 8735019
• 负责人: Daniel Enrique Jimenez
• 金额: $ 27.15万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-15 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8735019
• 关键词: Address; African American; Age; Anxiety; Anxiety Disorders; Applications Grants; Area; Asian Americans; Belief; Clinical; Community Health; Depressive disorder; Development; Development Plans; Diagnostic and Statistical Manual of Mental Disorders; Disadvantaged; Disease; Disease remission; Effectiveness; Elderly; Exercise; Foundations; Funding; Future; Health Alliance; Health Promotion; Health behavior change; High Prevalence; Hispanics; Individual; Intervention; Knowledge; Latino; Life; Major Depressive Disorder; Manuscripts; Measurable; Medical; Mental Depression; Mental Health; Mental Health Services; Mental disorders; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Methods; Minority Groups; National Institute of Mental Health; Obesity; Outcome; Participant; Peer Review; Physical Function; Physical activity; Pilot Projects; Population; Prevention; Prevention Research; Prevention approach; Preventive Intervention; Productivity; Psyche structure; Public Health; Randomized; Randomized Controlled Trials; Reporting; Request for Applications; Research; Research Personnel; Risk; Risk Factors; Safety; Self Efficacy; Services; Severities; Social Functioning; Symptoms; Testing; Universities; Work; base; career development; college; depressive symptoms; design; diabetes risk; ethnic minority population; experience; geriatric mental health; help-seeking behavior; high risk; innovation; medical schools; meetings; minor depressive disorder; prevent; psychoeducation; psychosocial; public health relevance; racial and ethnic; randomized trial; research and development; sedentary; skills; social stigma; subthreshold depression; therapy design

DESCRIPTION (provided by applicant): This proposal is for a K23 Mentored Patient Oriented Research Career Development Award that will prepare the candidate, Daniel Jimenez, become an independently funded researcher with expertise in health promotion/health behavior change interventions designed to prevent common mental illness (depression and anxiety) in at-risk racial/ethnic minority elderly. The candidate and his mentors at Dartmouth Medical School, Cambridge Health Alliance and the University of Pittsburgh have designed a career development plan, which is comprised of scholarly didactics and seminars, expert mentorship, hands-on experience at Dartmouth College, Harvard University, and the University of Pittsburgh as well as measurable productivity including peer- reviewed manuscripts and grant applications. His three career development aims are: 1) to gain expertise in the development of health promotion/health behavior change interventions to prevent common mental health disorders in high-risk older racial/ethnic minority populations; 2) to develop methodological expertise in depression and anxiety prevention research as a foundation for conducting health promotion/health behavior change research in racial/ethnic minority elderly; and 3) to gain increased knowledge on the effects of health promotion/health behavior change interventions on risk factors for depression/anxiety. Addressing these career development aims will provide the candidate with the skills and expertise to conduct the research plan in this proposal. A mixed methods approach will be used to develop and refine Happy Older Latinos are Active (HOLA), a physical activity intervention led by a community health worker, and to demonstrate feasibility, acceptability, and safety of the intervention in a randomized trial. This pilot study has three specific aims: 1) to develop and refine HOLA to address depression and anxiety prevention in a group of older Latinos with minor and subthreshold depression and anxiety; 2) to evaluate the feasibility and potential effectiveness of the newly refined HOLA compared to an enhanced psychoeducation condition with respect to: (a.) depression and anxiety prevention and (b.) depression and anxiety severity; 3) to evaluate the feasibility and potential effectiveness of HOLA compared to enhanced psychoeducation with respect to physical and psychosocial functioning. The development of a health promotion intervention designed to prevent common mental disorders could be a means of addressing multiple disparities (e.g. mental health outcomes, mental health service use, stigma) among racial/ethnic minority elderly. Should these results prove to be promising, a future R01 proposal for an adequately powered, randomized control trial will be submitted. Additionally, the results of this study could have implications fo other high risk, highly disadvantaged populations who could benefit from the proposed health promotion intervention in the service of preventing common and disabling mental disorders.

描述（由申请人提供）：该提案是为K23指导的以患者为导向的研究职业发展奖，该奖项将为候选人丹尼尔·希门尼斯做好准备，成为一名独立资助的研究人员，具有健康促进/健康行为改变干预措施的专业知识，旨在预防常见的精神疾病（抑郁和焦虑）在高危种族/少数民族老年人中。候选人及其在达特茅斯医学院、剑桥健康联盟和匹兹堡大学的导师设计了职业发展计划，其中包括学术教学和研讨会、专家指导、在达特茅斯学院、哈佛大学和匹兹堡大学的实践经验以及可衡量的生产力，包括同行评审的手稿和资助申请。他的三个职业发展目标是：1）获得健康促进/健康行为改变干预措施开发方面的专业知识，以预防高危老年种族/少数民族人群中常见的心理健康障碍; 2）发展抑郁和焦虑预防研究的方法学专业知识，作为在种族/少数民族老年人中进行健康促进/健康行为改变研究的基础;以及3）获得更多关于健康促进/健康行为改变干预对抑郁/焦虑危险因素的影响的知识。实现这些职业发展目标将为候选人提供执行本提案中研究计划的技能和专业知识。将使用混合方法来开发和完善“快乐老年拉丁裔活跃”（HOLA），这是一项由社区卫生工作者领导的身体活动干预措施，并在随机试验中证明干预措施的可行性、可接受性和安全性。这项试点研究有三个具体目标：1）开发和完善HOLA，以解决抑郁症和焦虑症的一组老年人与轻微和阈下抑郁症和焦虑症的预防; 2）评估的可行性和潜在的有效性，新完善的HOLA相比，增强心理教育条件方面：（a）。抑郁和焦虑预防和（B.）抑郁和焦虑的严重程度; 3）评估HOLA与增强心理教育在身体和心理社会功能方面的可行性和潜在有效性。制定旨在预防常见精神障碍的健康促进干预措施，可以解决少数种族/族裔老年人之间的多重差异（例如，精神健康结果，精神健康服务的使用，耻辱）。如果这些结果被证明是有希望的，未来将提交一项具有充分把握度的随机对照试验的R 01提案。此外，这项研究的结果可能会影响其他高风险，高度弱势群体谁可以受益于拟议的健康促进干预服务，预防常见的和致残的精神疾病。