Exercise to prevent depression and anxiety in older Hispanics

锻炼可预防老年西班牙裔人的抑郁和焦虑

• 批准号: 8580845
• 负责人: Daniel Enrique Jimenez
• 金额: $ 6.65万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-15 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8580845
• 关键词: Address; African American; Age; Anxiety; Anxiety Disorders; Applications Grants; Area; Asian Americans; Belief; Clinical; Community Health; Depressive disorder; Development; Development Plans; Diagnostic and Statistical Manual; Disadvantaged; Disease; Disease remission; Effectiveness; Elderly; Exercise; Foundations; Funding; Future; Health Alliance; Health Promotion; Health behavior change; High Prevalence; Hispanics; Individual; Intervention; Knowledge; Latino; Life; Major Depressive Disorder; Manuscripts; Measurable; Medical; Mental Depression; Mental Health; Mental Health Services; Mental disorders; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Methods; Minority Groups; National Institute of Mental Health; Obesity; Outcome; Participant; Peer Review; Physical Function; Physical activity; Pilot Projects; Population; Prevention; Prevention Research; Prevention approach; Preventive Intervention; Productivity; Psyche structure; Public Health; Randomized; Randomized Controlled Trials; Reporting; Request for Applications; Research; Research Personnel; Risk; Risk Factors; Safety; Self Efficacy; Services; Severities; Social Functioning; Symptoms; Testing; Universities; Work; base; career development; college; depressive symptoms; design; diabetes risk; ethnic minority population; experience; geriatric mental health; help-seeking behavior; high risk; innovation; medical schools; meetings; minor depressive disorder; prevent; psychoeducation; psychosocial; public health relevance; racial and ethnic; randomized trial; research and development; sedentary; skills; social stigma; subthreshold depression; therapy design

DESCRIPTION (provided by applicant): This proposal is for a K23 Mentored Patient Oriented Research Career Development Award that will prepare the candidate, Daniel Jimenez, become an independently funded researcher with expertise in health promotion/health behavior change interventions designed to prevent common mental illness (depression and anxiety) in at-risk racial/ethnic minority elderly. The candidate and his mentors at Dartmouth Medical School, Cambridge Health Alliance and the University of Pittsburgh have designed a career development plan, which is comprised of scholarly didactics and seminars, expert mentorship, hands-on experience at Dartmouth College, Harvard University, and the University of Pittsburgh as well as measurable productivity including peer- reviewed manuscripts and grant applications. His three career development aims are: 1) to gain expertise in the development of health promotion/health behavior change interventions to prevent common mental health disorders in high-risk older racial/ethnic minority populations; 2) to develop methodological expertise in depression and anxiety prevention research as a foundation for conducting health promotion/health behavior change research in racial/ethnic minority elderly; and 3) to gain increased knowledge on the effects of health promotion/health behavior change interventions on risk factors for depression/anxiety. Addressing these career development aims will provide the candidate with the skills and expertise to conduct the research plan in this proposal. A mixed methods approach will be used to develop and refine Happy Older Latinos are Active (HOLA), a physical activity intervention led by a community health worker, and to demonstrate feasibility, acceptability, and safety of the intervention in a randomized trial. This pilot study has three specific aims: 1) to develop and refine HOLA to address depression and anxiety prevention in a group of older Latinos with minor and subthreshold depression and anxiety; 2) to evaluate the feasibility and potential effectiveness of the newly refined HOLA compared to an enhanced psychoeducation condition with respect to: (a.) depression and anxiety prevention and (b.) depression and anxiety severity; 3) to evaluate the feasibility and potential effectiveness of HOLA compared to enhanced psychoeducation with respect to physical and psychosocial functioning. The development of a health promotion intervention designed to prevent common mental disorders could be a means of addressing multiple disparities (e.g. mental health outcomes, mental health service use, stigma) among racial/ethnic minority elderly. Should these results prove to be promising, a future R01 proposal for an adequately powered, randomized control trial will be submitted. Additionally, the results of this study could have implications fo other high risk, highly disadvantaged populations who could benefit from the proposed health promotion intervention in the service of preventing common and disabling mental disorders.

描述（由申请人提供）：本提案为K23指导患者导向研究职业发展奖，将使候选人Daniel Jimenez成为一名独立资助的研究人员，其专长是健康促进/健康行为改变干预措施，旨在预防高危种族/少数民族老年人的常见精神疾病（抑郁和焦虑）。候选人和他在达特茅斯医学院、剑桥健康联盟和匹兹堡大学的导师设计了一个职业发展计划，其中包括学术教学和研讨会、专家指导、达特茅斯学院、哈佛大学和匹兹堡大学的实践经验，以及可衡量的生产力，包括同行评审的手稿和资助申请。他的三个职业发展目标是：1)在健康促进/健康行为改变干预措施的发展方面获得专业知识，以预防高危老年种族/少数民族人群中常见的精神健康障碍；2)发展预防抑郁和焦虑研究的方法学专业知识，为开展少数民族老年人健康促进/健康行为改变研究奠定基础；3)进一步了解健康促进/健康行为改变干预措施对抑郁/焦虑危险因素的影响。解决这些职业发展目标将为候选人提供执行本提案中研究计划的技能和专业知识。将采用混合方法开发和完善由社区卫生工作者领导的身体活动干预“快乐拉美老年人活跃”（HOLA），并在一项随机试验中证明该干预的可行性、可接受性和安全性。本试点研究有三个具体目的：1)发展和完善HOLA，以解决患有轻度和阈下抑郁和焦虑的老年拉美裔人群的抑郁和焦虑预防问题；2)评估新改进的HOLA与增强的心理教育条件在以下方面的可行性和潜在有效性：(a)抑郁和焦虑的预防；(b)抑郁和焦虑的严重程度；3)与增强心理教育相比，评估HOLA在身体和社会心理功能方面的可行性和潜在有效性。制定旨在预防常见精神障碍的健康促进干预措施，可作为解决种族/族裔少数群体老年人之间多重差异（例如精神健康结果、精神卫生服务的使用、耻辱）的一种手段。如果这些结果被证明是有希望的，未来的R01建议将提交一个足够有力的随机对照试验。此外，这项研究的结果可能会对其他高风险、高度弱势群体产生影响，他们可能会从拟议的健康促进干预措施中受益，以预防常见和致残性精神障碍。