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Investigating a role for TAM receptor signaling in demyelination

Investigating a role for TAM receptor signaling in demyelination
研究 TAM 受体信号传导在脱髓鞘中的作用
批准号:
nhmrc : 1031450
负责人:
Dr Judith Field
金额:
$29.63万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31

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中文摘要
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英文摘要
In Multiple Sclerosis brain cells are damaged and myelin is lost in a process known as demyelination. Two proteins, called Gas6 and Protein S, can influence cells involved in MS, by signalling through proteins called TAMs. We have shown that Gas6 can affect the severity of demyelination in mice, and that TAMs can affect the response of cells to interferon-beta, a major MS treatment. We plan to further study the effects of these proteins during demyelination, and their interaction with interferon-beta.
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Investigating the archaeology of human settlement in the highlands of PNG
  • 批准号:
    DP150102753
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $33.43万
  • 财政年份:
    2015
  • 负责人:
    Dr Judith Field
  • 依托单位:
Functional assessment of CD40 in the development of Multiple Sclerosis
  • 批准号:
    nhmrc : 1065157
  • 项目类别:
    Project Grants
  • 资助金额:
    $34.8万
  • 财政年份:
    2014
  • 负责人:
    Dr Judith Field
  • 依托单位:
The dynamics of human environment interactions in late Pleistocene and Holocene highland New Guinea: a study of the Ivane valley.
  • 批准号:
    DP110102828
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $13.99万
  • 财政年份:
    2011
  • 负责人:
    Dr Judith Field
  • 依托单位:
First Australians, Last Megafauna? Modern Approaches To A Prehistoric Puzzle.
  • 批准号:
    DP0557923
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $33.35万
  • 财政年份:
    2005
  • 负责人:
    Dr Judith Field
  • 依托单位:
国内基金
海外基金
PfAP2-R介导的PfCRT转录调控在恶性疟原虫对喹啉类药物抗性中的作用及机制研究
Sestrin2抑制内质网应激对早产儿视网膜病变的调控作用及其机制研究
  • 批准号:
    82371070
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2023
  • 负责人:
    赵培泉
  • 依托单位: