Investigating a tumour suppressor in haematopoiesis and lymphoblastic leukaemia

研究造血和淋巴细胞白血病中的肿瘤抑制因子

• 批准号: nhmrc : GNT1161111
• 金额: $ 76.66万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigating-tumour-suppressor-lymphoblastic-leukaemia/1379157
• 关键词: Investigating; tumour; suppressor; haematopoiesis; lymphoblastic

Acute lymphoblastic leukaemia is the most common childhood cancer. Current treatment of children with cancer unfortunately often results in severe treatment-related disease, emphasising the need for novel therapies. In the proposed project, we will examine the molecular and cellular functions of a gene commonly mutated in acute lymphoblastic leukaemia with the aim of identifying underlying molecular mechanisms that may allow the development of new therapeutic options in the future.

急性淋巴细胞白血病是最常见的儿童癌症。不幸的是，目前对癌症儿童的治疗经常导致严重的治疗相关疾病，这强调了对新疗法的需求。在拟议的项目中，我们将检查急性淋巴细胞白血病中常见突变基因的分子和细胞功能，目的是确定可能在未来开发新治疗方案的潜在分子机制。