Continued Development, Evaluation and Testing of Sesame LIMS

描述(由申请人提供)：SESAME是威斯康星大学麦迪逊分校开发的一个通用的、免费提供的云实验室信息管理系统(LIMS)，目前正在世界各地的多个实验室用于小规模和大型应用。它支持收集、组织、处理和分析来自各种来源的信息，包括数据库、实验室科学家、实验室仪器和软件包。SESAME LIMS已证明其在结构和功能蛋白质组学研究、传统蛋白质化学或分子生物学实验室以及共用仪器设施管理方面的价值。它使合作者能够参与研究项目，具有同等的信息访问权限以及输入结果和处理数据的能力，而不受地点的限制(给定互联网访问权限)。SESAME软件是用Java编写的，使用CORBA作为中间件，并与关系数据库管理系统接口。所要求的资金将用于支持SESAME LIMS的继续开发、评估和测试，并提供其“软件即服务”的免费实例。软件开发的目的将是(1)提高SESAME框架的效率和灵活性，(2)使用户更容易根据自己的需要定制软件，(3)改进现有的应用程序，并根据用户的需要开发新的应用程序。其目标是让更多的结构生物学家、分子生物学家和生物化学家可以使用该软件。作为这项工作的一部分，我们将创建可重复使用的对象，并为开发人员提供Sesame的应用程序编程接口，以便他们可以创建Sesame客户端来解决他们实验室特有的问题。我们将确保该软件在多种平台上运行，支持各种关系数据库管理系统，并为所支持的平台提供免费的解决方案堆栈。将保留向外部数据储存库导出数据和从外部数据储存库导入数据的方法并使其保持最新。我们将继续开发可通过Web访问的用户帮助页面和视频教程。为各种SESAME应用程序开发的模式和受控词汇表将在Web上提供给感兴趣的用户。所有软件都将是开源的。

DESCRIPTION (provided by applicant): Sesame is a versatile, freely available, cloud laboratory information management system (LIMS) developed at the University of Wisconsin-Madison that is in use in multiple laboratories around the world both for small- scale and large-scale applications. It supports the gathering, organization, processing, and analysis of information from a variety of sources, including databases, bench scientists, laboratory instrumentation, and software packages. The Sesame LIMS has proved its value in structural and functional proteomics investigations, in traditional protein chemistry or molecular biology laboratories, and in management of shared instrumentation facilities. It enables collaborators to participate in a research project, with equivalent access to information and the ability to enter results and process data irrespective of location (given Internet access). The Sesame software is written in Java, uses CORBA as a middleware, and is interfaced to a relational database management system. The requested funds will be used to support the continued development, evaluation, and testing of the Sesame LIMS and to provide a freely available instance of it as 'software as a service'. The software development will be aimed at (1) improving the efficiency and flexibility of the Sesame framework, (2) making it easier for users to customize the software for their own needs, and (3) improving the existing applications and developing new ones in response to user needs. The goal is to make the software available to a larger clientele of structural biologists, molecular biologists, and biochemists. As part of this effort, we will creat reusable objects and provide an application programming interface to Sesame for developers, so they can create Sesame clients to solve problems specific to their laboratory. We will ensure that the software runs on a variety of platforms, supports a variety of relational database management systems, and that a free solution stack exists for the platforms supported. The methods for exporting and importing data to/from external data repositories will be maintained and kept up to date. We will continue to develop Web accessible user help pages and video tutorials. The schema and controlled vocabularies developed for various Sesame applications will be made available on the Web to interested users. All software will be open source.