Post-Doctoral Research Training in Genetic Epidemiology

描述（由申请人提供）：本次修订的博士后研究培训支持更新申请的主要目标是培养遗传流行病学领域的尖端独立科学家和未来的研究领导者。我们建议在多学科背景下进行这项研究，重点放在心血管疾病（CVD）和CVD危险因素以及与心脏、肺和血液疾病相关的其他复杂特征的实质性应用方向上。我们已经与我们机构的心脏病学奖学金项目达成了合作安排，这样我们就可以在博士之外积极招募医学博士（以及医学博士/博士）。我们认为华盛顿大学的研究环境非常适合开展心血管遗传流行病学的研究。这个年轻项目的基石是强调在经验丰富的导师的监督下，对每位学员进行高强度和持续的个性化培训。事实上，强调个性化训练是其标志之一。它的核心是一个个性化的培训途径（ITP），由项目主管、学员的导师和学员为每个学员开发。个别受训者的ITP将反映他/她的教育背景、以前的研究经验（如果有的话）、受训者的特定研究兴趣，并将满足课程需求以及他/她所需的研究经验类型。项目主任和参与导师所倡导的研究和培训理念的重点是对研究心血管疾病和相关复杂特征的生理和病理生理过程所必需的遗传流行病学概念、原理和方法的清晰理解。我们正在申请资金，以继续支持每年4个名额（其中一半名额用于医学博士和医学博士/博士）。我们的建议通过混合和整合精心选择的教学培训，更强调直接的动手研究和拨款写作经验，来应对挑战。该培训项目的一大优势在于，所有的博士后学员都可以利用我院庞大的现有资源和丰富的跨学科培训环境，以及我院的GEMS和MSIBS硕士学位培训项目。拟议的博士后研究培训计划旨在培养未来的遗传流行病学家，以满足当前市场对心血管和其他生物医学研究的需求。华盛顿大学的研究培训环境非常出色，它还有一个独立的研究生事务办公室，负责照顾博士后学员和他们的特殊需求，并为他们提供支持。

DESCRIPTION (provided by applicant): The primary objective of this revised renewal application for post-doctoral research training support is to produce cutting edge independent scientists and future research leaders in genetic epidemiology. We are proposing to do this in a multidisciplinary setting with emphasis on substantive applied orientation in cardiovascular disease (CVD) and CVD risk factors and other complex traits related to heart, lung, and blood disorders. We have made partnership arrangements with cardiology fellowship programs at our institution so that we can actively recruit MDs (and MD/PhDs) in addition to PhDs. We believe that the research environment at Washington University is outstanding for carrying out research in cardiovascular genetic epidemiology. The cornerstone of this young program is its emphasis on intense and sustained individualized training of each trainee under the supervision of an experienced preceptor. Indeed, emphasis on individualized training is one of its hallmarks. Its centerpiece is an Individualized Training Pathway (ITP) developed for each trainee by the Program Director, the trainee's preceptor(s), and the trainee. An individual trainee's ITP will reflect his/her educational background, the previous research experience if any, the particular research interests of the trainee, and will address the curriculum needs as well as the type of research experience he/she needs. The focus of the research and training philosophy advocated by the Program Director and the participating preceptors is a clear understanding of the concepts, principles, and methods of genetic epidemiology necessary for investigating the physiological and pathophysiological processes that underlie CVD and related complex traits. We are requesting funds for continuing to support 4 slots each year (with half the slots devoted to MDs and MD/PhDs). Our proposal rises to the challenge by blending and integrating carefully chosen didactic training with greater emphasis on a direct hands-on research and grant writing experience. One of the great strengths of this training program is that the vast established resources and rich interdisciplinary training environment of the entire DBBS, as well as those of our GEMS and MSIBS masters degree training programs are available to all post-doctoral trainees in this program. The proposed post-doctoral research training program aspires to produce future genetic epidemiologists in much demand in the current market place for pursuing cardiovascular and other biomedical research. The research training environment at Washington University is outstanding, which also has a separate Office of Post Graduate Affairs to look after postdoctoral trainees and their special needs and serve as their advocate.