Basic Science Training Program in the Neurobiology of Mental Illness

描述（由申请人提供）：在精神疾病的神经生物学（NMI）在UT西南的基础科学培训计划的目的是提供跨学科的，基本的以疾病为导向的研究培训直接相关的精神疾病的博士前和博士后研究员。这个应用程序继续支持我们的NMI培训计划在UT西南是直接响应NIMH的呼吁更多的基础科学家在广泛的多样化，创新的基础研究，密切告知我们的理解和精神疾病的治疗培训。除了全国范围内缺乏基础科学研究人员探索神经精神疾病的神经生物学之外，相反，缺乏临床训练的个人从事精神疾病的基础研究，从而减少了该领域迫切需要的交叉对话。精神障碍的复杂性需要一种跨学科的方法来阐明潜在的疾病机制，并开发更好的诊断措施，治疗方法，并最终治愈。 我们的NMI培训计划具有众多优势，包括：a）UT西南部的优秀环境，在其中进行基础，跨学科的生物医学研究; B）UT西南神经科学界的智力强度和紧密联系的性质; c）在多个学术部门进行的基础神经生物学研究的整合; d）在UT西南部异常强大的基础，探索抑郁症，精神分裂症和自闭症的基本基础; e）在精神疾病的基础科学与临床计划的预先存在的整合; g）计算初级和高级导师之间的互动，从而确保初级导师也将从培训计划中受益，并在未来几年继续从事心理健康研究;和h）新颖的、以预防为导向的培训组成部分，例如动手神经生理学和人类神经解剖学实验室，新的临床相关性研讨会，以及每个实习生的博士论文委员会中有一名临床医生。

DESCRIPTION (provided by applicant): The Basic Science Training Program in the Neurobiology of Mental Illness (NMI) at UT Southwestern is designed to provide interdisciplinary, basic disease-oriented research training directly relevant to mental illness to predoctoral and postdoctoral fellows. This application for continued support for our NMI Training Program at UT Southwestern is a direct response to NIMH's call for more basic scientists trained in a broad range of diverse, innovative basic research that closely informs our understanding and treatment of mental illness. In addition to the paucity of basic science researchers nationwide exploring the neurobiology of neuropsychiatric diseases, there is, conversely, a dearth of clinically-trained individuals pursuing basic research in mental illness, thus diminishing the very cross talk that is urgently needed in this field. The complexity of mental disorders demands an interdisciplinary approach to illuminate underlying disease mechanisms and to develop better diagnostic measures, treatments, and ultimately cures. Our NMI training program has numerous strengths, including: a) the outstanding environment at UT Southwestern in which to conduct basic, interdisciplinary biomedical research; b) the intellectual intensity and close-knit nature of the UT Southwestern neuroscience community; c) the integration of fundamental neurobiological research performed in multiple academic divisions; d) the unusually strong foundation at UT Southwestern to explore fundamental underpinnings of depression, schizophrenia and autism; e) the preexisting integration of basic science with clinical programs in mental illness; f) the breadth and depth of our potential trainees; g) calculated interactions between junior and senior mentors, thus ensuring that junior mentors will also benefit from the Training Program and will remain in mental health research in future years; and h) novel, translationally-oriented training components, such as hands-on neurophysiology and human neuroanatomy laboratories, a new Clinical Correlations Seminar, and the presence of a clinician on each trainee's doctoral thesis committee.