Adenovirus

腺病毒

• 批准号: 8703146
• 负责人: Steven M Anderson
• 金额: $ 9.18万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8703146
• 关键词: Adenovirus Vector; Adenoviruses; Breast Epithelial Cells; Funding; Gland; In Vitro; Inflammation; Laboratories; System; Technology; Virus; Work; in vivo; mammary gland development

This core provides adenovirus vectors for both in vitro and in vivo studies. Intraductal delivery resulting in transduction of mammary epithelial cells in the intact gland in the absence of inflammation has been extensively developed [26]. Although the majority of the experimental work that went into developing this system was conducted in the Neville laboratory, the McManaman laboratory has made extensive use of this technology during the present funding period. In the new proposal, all projects of plan to make use of this technology. A full list of the viruses currently available is presented in the Core Description.

该核心为体外和体内研究提供了腺病毒载体。导管内分娩导致乳腺上皮细胞在没有炎症的完整腺体中的转导已经广泛发展[26]。虽然开发这个系统的大部分实验工作是在内维尔实验室进行的，但麦克马纳曼实验室已经广泛使用了这个系统