Smart Wearable Flex-circuit for Continuous Transdermal Alcohol Monitoring

 描述（由申请人提供）：Seacoast Science，Inc.正计划开发，认证，然后商业化的舒适穿着，非侵入性监测器，预测生理酒精损害人体的基础上，透皮乙醇测量。使用最佳的小型化方法，我们将把显示器制作成衣服、手镯、吊坠或装饰配件。这种监测器将立即用于打击酗酒现象。这些监测器是基于催化酒精传感器，已被证明是可靠的呼吸测醉器。这项工作充分利用了Seacoast在为各种应用设计酒精检测器方面的经验，沿着将传感器嵌入衣服中。影响：酒精滥用和损害对美国和全球的生命和财产造成重大损害。美国疾病控制中心发布的一份报告称，2006年美国酗酒导致88，000人死亡，造成2235亿美元的财政损失。美国国家公路运输安全管理局报告说，2013年有10,076人在与酒精有关的机动车事故中死亡。在世界范围内，世界卫生组织报告每年有330万人死于酒精滥用，占所有死亡人数的5.9%。总体而言，全球疾病和伤害负担的5.1%可归因于酒精，以残疾调整生命年（DALLS）衡量。饮酒会导致生命早期的死亡和残疾。在20 - 39岁年龄组中，约25%的死亡可归因于酒精。

 DESCRIPTION (provided by applicant): Seacoast Science, Inc. is proposing to develop, certify, and then commercialize comfort- wear, non-invasive monitors that predict physiological alcohol impairment in humans based on transdermal ethanol measurements. Using best-practice miniaturization methods, we will build the monitors into clothing, arm bracelets, pendants or decorative accessories. Such monitors will have immediate application in the effort to combat alcohol misuse. These monitors are based on catalytic alcohol sensors that have proven to be reliable in breathalyzers. The work leverages Seacoast's experience in designing alcohol detectors for various applications along with work embedding sensors in articles of clothing. Impact: Alcohol abuse and impairment cause significant damage to lives and property in the US and globally. The Centers for Disease Control published a report that alcohol abuse in the United States caused 88,000 deaths and resulted in $223.5 billion financial cost for 2006. The National Highway Transportation Safety Administration reported 10,076 fatalities in alcohol- involved motor vehicle crashes in 2013. Worldwide, the World Health Organization reports 3.3 million deaths every year resulting from alcohol abuse, representing 5.9 % of all deaths. Overall 5.1 % of the global burden of disease and injury is attributable to alcohol, as measured in disability-adjusted life years (DALYs). Alcohol consumption causes death and disability relatively early in life. In the age group 20 - 39 years, approximately 25 % of the total deaths ar alcohol-attributable.