Reinforcement as a Prospective Predictor of Real-time Alcohol Abuse Following Bariatric Surgery

摘要 最近的研究清楚地表明，与手术前相比，减肥手术后的患者 酒精使用障碍和酒精摄入量增加的风险增加。了解这些机制， 导致这些负面临床结果的原因具有相当大的科学和临床重要性。在 目前的研究，我们建议调查在何种程度上的变化，在强化酒精导致 肥胖手术后患者的酒精摄入量增加。我们将采用瞬间自然主义评估， 客观的连续酒精测量，以及仔细评估强化的实验室方法 使用一种基于经验支持的行为经济学方法。此外，这项研究的目的是作为一个 一项前瞻性纵向研究，将对减肥手术患者进行随访，随访时间为术后1年至2年。 手术

ABSTRACT Recent research has clearly shown that when compared to before surgery, post-bariatric surgery patients are at increased risk for alcohol use disorders and increased alcohol intake. Understanding the mechanisms that contribute to these negative clinical outcomes is of considerable scientific and clinical importance. In the present study, we propose to investigate the extent to which changes in the reinforcement of alcohol lead to increased alcohol intake in post-bariatric surgery patients. We will employ momentary naturalistic assessment, objective continuous alcohol measurement, and laboratory methodology to carefully assess reinforcement using an empirically supported behavior economics-based measure. Additionally, this study is designed as a prospective, longitudinal investigation that will follow bariatric surgery patients from one year to two years after surgery.