Reinforcement as a Prospective Predictor of Real-time Alcohol Abuse Following Bariatric Surgery

摘要 最近的研究清楚地表明，与手术前相比，减肥手术后的患者 酒精使用障碍和酒精摄入量增加的风险增加。了解以下机制 造成这些负面的临床结果具有相当重要的科学和临床意义。在 目前的研究，我们建议调查酒精强化的变化导致的程度 减肥手术后患者酒精摄入量增加。我们将采用瞬间的自然主义评估， 目的连续酒精测量和实验室方法学仔细评估强化 使用经验支持的基于行为经济学的衡量标准。此外，这项研究被设计为一种 对减肥手术患者进行一年至两年的前瞻性纵向调查 做手术。

ABSTRACT Recent research has clearly shown that when compared to before surgery, post-bariatric surgery patients are at increased risk for alcohol use disorders and increased alcohol intake. Understanding the mechanisms that contribute to these negative clinical outcomes is of considerable scientific and clinical importance. In the present study, we propose to investigate the extent to which changes in the reinforcement of alcohol lead to increased alcohol intake in post-bariatric surgery patients. We will employ momentary naturalistic assessment, objective continuous alcohol measurement, and laboratory methodology to carefully assess reinforcement using an empirically supported behavior economics-based measure. Additionally, this study is designed as a prospective, longitudinal investigation that will follow bariatric surgery patients from one year to two years after surgery.